Detailed information    

insolico Bioinformatically predicted

Overview

Name   braS   Type   Regulator
Locus tag   NW957_RS12995 Genome accession   NZ_CP102977
Coordinates   2625839..2626726 (-) Length   295 a.a.
NCBI ID   WP_000143420.1    Uniprot ID   A0A2S6DP21
Organism   Staphylococcus aureus strain 27-G-H     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2620839..2631726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW957_RS12965 (NW957_12965) - 2620855..2620947 (+) 93 WP_010956583.1 hypothetical protein -
  NW957_RS12970 (NW957_12970) - 2621055..2621552 (-) 498 WP_001065268.1 glutathione peroxidase -
  NW957_RS12975 (NW957_12975) - 2621562..2621822 (-) 261 WP_001789910.1 hypothetical protein -
  NW957_RS12980 (NW957_12980) - 2622204..2622317 (-) 114 WP_011447078.1 hypothetical protein -
  NW957_RS12985 (NW957_12985) - 2622978..2624978 (-) 2001 WP_165468985.1 ABC transporter permease -
  NW957_RS12990 (NW957_12990) - 2624975..2625730 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  NW957_RS12995 (NW957_12995) braS 2625839..2626726 (-) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  NW957_RS13000 (NW957_13000) braR 2626737..2627402 (-) 666 WP_165468984.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  NW957_RS13005 (NW957_13005) - 2627428..2627628 (-) 201 WP_000604727.1 hypothetical protein -
  NW957_RS13010 (NW957_13010) - 2627826..2629250 (+) 1425 WP_000953744.1 alkaline phosphatase -
  NW957_RS13505 - 2629310..2629411 (-) 102 WP_000731976.1 SE2200 family small protein -
  NW957_RS13020 (NW957_13020) - 2629533..2629988 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  NW957_RS13025 (NW957_13025) - 2630233..2630994 (-) 762 WP_000323441.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 295 a.a.        Molecular weight: 34045.32 Da        Isoelectric Point: 5.8962

>NTDB_id=721060 NW957_RS12995 WP_000143420.1 2625839..2626726(-) (braS) [Staphylococcus aureus strain 27-G-H]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide


Download         Length: 888 bp        

>NTDB_id=721060 NW957_RS12995 WP_000143420.1 2625839..2626726(-) (braS) [Staphylococcus aureus strain 27-G-H]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(191-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DP21

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braS Staphylococcus aureus N315

99.322

100

0.993