Detailed information NTG0721054

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW957_RS09195
• Genome accession: NZ_CP102977
• Coordinates: 1889613..1890656 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 27-G-H
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1884613..1895656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW957_RS09165 (NW957_09165)	-	1885035..1886291 (-)	1257	WP_001793428.1	aminopeptidase	-
NW957_RS09170 (NW957_09170)	-	1886294..1886494 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW957_RS09175 (NW957_09175)	-	1886641..1887105 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW957_RS09180 (NW957_09180)	-	1887112..1887387 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW957_RS09185 (NW957_09185)	-	1887665..1888882 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
NW957_RS09190 (NW957_09190)	vraR	1888994..1889623 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
NW957_RS09195 (NW957_09195)	vraS	1889613..1890656 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW957_RS09200 (NW957_09200)	liaF	1890653..1891354 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NW957_RS09205 (NW957_09205)	-	1891369..1891755 (-)	387	WP_001110179.1	hypothetical protein	-
NW957_RS09210 (NW957_09210)	map	1891972..1892730 (-)	759	WP_000636138.1	type I methionyl aminopeptidase	-
NW957_RS09215 (NW957_09215)	-	1893320..1894306 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW957_RS09220 (NW957_09220)	-	1894737..1895150 (-)	414	WP_001670387.1	hypothetical protein	-
NW957_RS09225 (NW957_09225)	-	1895179..1895289 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=721054 NW957_RS09195 WP_001017131.1 1889613..1890656(-) (vraS) [Staphylococcus aureus strain 27-G-H]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=721054 NW957_RS09195 WP_001017131.1 1889613..1890656(-) (vraS) [Staphylococcus aureus strain 27-G-H]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1