Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NW953_RS09555 Genome accession   NZ_CP102975
Coordinates   1960376..1961005 (-) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain 16CS0209     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1955376..1966005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW953_RS09525 (NW953_09525) - 1955796..1956326 (-) 531 WP_000184383.1 acyl-CoA thioesterase -
  NW953_RS09530 (NW953_09530) - 1956416..1957672 (-) 1257 WP_001793983.1 aminopeptidase -
  NW953_RS09535 (NW953_09535) - 1957675..1957875 (-) 201 WP_000180460.1 DUF1128 family protein -
  NW953_RS09540 (NW953_09540) - 1958022..1958486 (+) 465 WP_000228670.1 low molecular weight protein-tyrosine-phosphatase -
  NW953_RS09545 (NW953_09545) - 1958493..1958768 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  NW953_RS09550 (NW953_09550) - 1959046..1960263 (+) 1218 WP_000037081.1 YihY/virulence factor BrkB family protein -
  NW953_RS09555 (NW953_09555) vraR 1960376..1961005 (-) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  NW953_RS09560 (NW953_09560) vraS 1960995..1962038 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  NW953_RS09565 (NW953_09565) liaF 1962035..1962736 (-) 702 WP_061742253.1 cell wall-active antibiotics response protein LiaF -
  NW953_RS09570 (NW953_09570) - 1962751..1963014 (-) 264 Protein_1842 hypothetical protein -
  NW953_RS09575 (NW953_09575) - 1963023..1963970 (-) 948 WP_000121214.1 IS30-like element ISSau1 family transposase -
  NW953_RS09580 (NW953_09580) - 1964083..1964211 (-) 129 Protein_1844 hypothetical protein -
  NW953_RS09585 (NW953_09585) map 1964428..1965186 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=721012 NW953_RS09555 WP_000153535.1 1960376..1961005(-) (vraR) [Staphylococcus aureus strain 16CS0209]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=721012 NW953_RS09555 WP_000153535.1 1960376..1961005(-) (vraR) [Staphylococcus aureus strain 16CS0209]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATATTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373