Detailed information    

insolico Bioinformatically predicted

Overview


Name   comK/comK1   Type   Regulator
Locus tag   NW975_RS04510 Genome accession   NZ_CP102971
Coordinates   955903..956472 (-) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain 08-G-E     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context


Location: 950903..961472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW975_RS04490 (NW975_04490) - 952408..953766 (+) 1359 WP_258413306.1 TrkH family potassium uptake protein -
  NW975_RS04495 (NW975_04495) - 953905..955416 (+) 1512 WP_258414804.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  NW975_RS04510 (NW975_04510) comK/comK1 955903..956472 (-) 570 WP_000287265.1 competence protein ComK Regulator
  NW975_RS04515 (NW975_04515) - 956682..956900 (+) 219 WP_258414805.1 IDEAL domain-containing protein -
  NW975_RS04520 (NW975_04520) - 956981..957967 (-) 987 WP_000668823.1 lipoate--protein ligase -
  NW975_RS04525 (NW975_04525) - 958166..958342 (+) 177 WP_000214898.1 YkvS family protein -
  NW975_RS04530 (NW975_04530) - 958357..958959 (+) 603 WP_001033867.1 CPBP family glutamic-type intramembrane protease -
  NW975_RS04535 (NW975_04535) - 959276..959338 (+) 63 WP_228764722.1 hypothetical protein -
  NW975_RS04540 (NW975_04540) - 959976..960260 (+) 285 WP_258410543.1 lactococcin 972 family bacteriocin -

Sequence


Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=720863 NW975_RS04510 WP_000287265.1 955903..956472(-) (comK/comK1) [Staphylococcus aureus strain 08-G-E]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=720863 NW975_RS04510 WP_000287265.1 955903..956472(-) (comK/comK1) [Staphylococcus aureus strain 08-G-E]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGCGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGCAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTTACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains


Predicted by InterproScan.

(5-156)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1

  comK/comK1 Staphylococcus aureus N315

100

100

1