Detailed information NTG0720804

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW965_RS09215
• Genome accession: NZ_CP102968
• Coordinates: 1905497..1906540 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 13-G-52
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1900497..1911540

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW965_RS09185 (NW965_09185)	-	1900918..1902174 (-)	1257	WP_001793428.1	aminopeptidase	-
NW965_RS09190 (NW965_09190)	-	1902177..1902377 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW965_RS09195 (NW965_09195)	-	1902524..1902988 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW965_RS09200 (NW965_09200)	-	1902995..1903270 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW965_RS09205 (NW965_09205)	-	1903548..1904765 (+)	1218	WP_045158466.1	YihY/virulence factor BrkB family protein	-
NW965_RS09210 (NW965_09210)	vraR	1904878..1905507 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
NW965_RS09215 (NW965_09215)	vraS	1905497..1906540 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW965_RS09220 (NW965_09220)	liaF	1906537..1907238 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
NW965_RS09225 (NW965_09225)	-	1907253..1907639 (-)	387	WP_001110179.1	hypothetical protein	-
NW965_RS09230 (NW965_09230)	map	1907856..1908614 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW965_RS09235 (NW965_09235)	-	1909141..1910127 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW965_RS09240 (NW965_09240)	-	1910316..1910729 (-)	414	WP_258412606.1	hypothetical protein	-
NW965_RS09245 (NW965_09245)	-	1910758..1910866 (-)	109	Protein_1778	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720804 NW965_RS09215 WP_001017131.1 1905497..1906540(-) (vraS) [Staphylococcus aureus strain 13-G-52]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720804 NW965_RS09215 WP_001017131.1 1905497..1906540(-) (vraS) [Staphylococcus aureus strain 13-G-52]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTACTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTGCAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1