Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   PUW71_RS06905 Genome accession   NZ_CP118053
Coordinates   1369273..1371063 (-) Length   596 a.a.
NCBI ID   WP_070812486.1    Uniprot ID   A0ABS3GD28
Organism   Streptococcus anginosus strain VSI40     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1364273..1376063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW71_RS06875 (PUW71_06875) - 1365063..1365515 (-) 453 WP_006268509.1 MarR family transcriptional regulator -
  PUW71_RS06880 (PUW71_06880) - 1365618..1366202 (-) 585 WP_274997737.1 uracil-DNA glycosylase family protein -
  PUW71_RS06890 (PUW71_06890) - 1366212..1367069 (-) 858 Protein_1322 SDR family oxidoreductase -
  PUW71_RS06895 (PUW71_06895) pepV 1367125..1368525 (-) 1401 WP_070584413.1 dipeptidase PepV -
  PUW71_RS06900 (PUW71_06900) - 1368548..1369150 (-) 603 Protein_1324 nitroreductase family protein -
  PUW71_RS06905 (PUW71_06905) uvrC 1369273..1371063 (-) 1791 WP_070812486.1 excinuclease ABC subunit UvrC Machinery gene
  PUW71_RS06910 (PUW71_06910) ptsP 1371214..1372947 (-) 1734 WP_024053004.1 phosphoenolpyruvate--protein phosphotransferase -
  PUW71_RS06915 (PUW71_06915) - 1372949..1373212 (-) 264 WP_003023815.1 phosphocarrier protein HPr -
  PUW71_RS06920 (PUW71_06920) nrdH 1373610..1373828 (+) 219 WP_003023812.1 glutaredoxin-like protein NrdH -

Sequence

Protein


Download         Length: 596 a.a.        Molecular weight: 68650.18 Da        Isoelectric Point: 9.5420

>NTDB_id=720801 PUW71_RS06905 WP_070812486.1 1369273..1371063(-) (uvrC) [Streptococcus anginosus strain VSI40]
MNNLIKSKLELLPTSPGCYIHKDKNGIIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIEDFEFIVTESNIEALLLEIN
LIKENRPKYNIMLKDDKSYPFIKITNEIYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPEKVCF
YYHIGQCRAHTVCHNDPHFFQEMAQEVADFLKGHDNKIIDELKGKMTSAAENMEFEKAAEYRNLLQSIATLRTKQRVIAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNMFPYYNDPDEDFLTYIGQFYQEKSHLIPNEILIPSDIDEIAVQAV
VDTKILKPQRGEKKQLVNLAIKNAQVSLQQKFDLLEKSVEKTQGAIENLGQLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FINGKPSKKDYRKYKIKTVIGPDDYASMREVIKRRYSRVMRDGLIPPDLIVIDGGQGQVNIAKDVIQNQLGLDIPIAGLQ
KNDKHQTHELLFGDPLKVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMRHFKSL
ANIKKASVDEIVEVGVPRKVAEAVQRKLRESRDKKE

Nucleotide


Download         Length: 1791 bp        

>NTDB_id=720801 PUW71_RS06905 WP_070812486.1 1369273..1371063(-) (uvrC) [Streptococcus anginosus strain VSI40]
ATGAACAACTTGATTAAATCAAAATTAGAATTGTTGCCTACTAGTCCAGGTTGCTATATTCATAAAGATAAAAATGGCAT
TATCATCTATGTCGGAAAAGCTAAGAATCTGCGTAATCGGGTGCGCTCTTATTTTCGTGGGAGCCATGATACTAAAACGG
AAGCACTGGTGTCTGAGATTGAGGATTTTGAGTTTATTGTCACGGAGTCTAATATTGAAGCCTTGCTGCTTGAAATCAAT
CTAATCAAGGAAAATCGGCCTAAATATAACATCATGCTTAAGGACGATAAGTCCTACCCTTTTATCAAAATCACCAATGA
GATATATCCGCGACTTATTATTACACGTCAGGTTAAAAAAGATGGTGGTTTATATTTTGGCCCGTATCCTGATGTAGGTG
CTGCGAATGAAATTAAGCGCCTGCTGGATCGCATTTTTCCTTTCCGCAAGTGTACCAATCCACCTGAGAAAGTTTGCTTC
TACTATCATATCGGACAGTGTCGAGCTCATACTGTCTGCCATAATGATCCACATTTCTTTCAAGAGATGGCTCAAGAAGT
AGCAGATTTCCTCAAAGGTCATGATAATAAGATTATTGATGAATTGAAAGGAAAAATGACTAGTGCTGCTGAAAATATGG
AATTTGAAAAAGCGGCTGAATACCGAAATTTGCTTCAAAGTATTGCGACACTTCGCACCAAGCAACGAGTGATAGCAAAG
GATTTACAGAATCGGGATGTCTTTGGATATTATGTGGACAAAGGATGGATGTGTGTACAGGTTTTCTTTGTCCGTCAAGG
AAAACTCATTGAGCGAGATGTAAATATGTTTCCTTATTACAATGACCCTGACGAGGATTTTCTGACCTATATTGGTCAAT
TTTATCAGGAAAAATCTCATCTGATTCCCAATGAAATTTTGATTCCATCTGATATTGATGAAATAGCTGTTCAGGCTGTG
GTGGATACGAAGATTCTCAAACCTCAGCGAGGAGAGAAGAAACAGCTGGTTAATTTGGCTATTAAAAATGCGCAAGTTAG
TTTGCAGCAGAAGTTTGATTTGTTGGAGAAATCTGTTGAAAAAACACAGGGAGCTATTGAAAATCTAGGTCAGTTGCTCA
ATATTCCCACTCCAGTTCGGATTGAATCGTTTGATAATTCCAATATTATGGGAACAAGTCCTGTTTCAGCTATGGTGGTT
TTTATCAATGGCAAACCCAGCAAAAAAGATTATCGCAAGTATAAGATTAAGACAGTTATCGGTCCTGATGACTATGCTAG
TATGCGAGAAGTGATTAAGCGCCGTTACAGTCGGGTTATGCGAGATGGTTTAATACCGCCTGATCTTATTGTCATTGACG
GTGGTCAGGGTCAAGTCAATATTGCTAAAGACGTCATTCAAAATCAATTAGGGTTAGATATTCCTATCGCTGGTTTGCAA
AAAAATGACAAGCACCAGACGCATGAATTGCTCTTTGGCGATCCTTTGAAAGTGGTTGAGTTATCTCGCAATTCGCAGGA
ATTTTTCCTCTTACAACGCATTCAAGATGAGGTGCACCGCTTTGCCATTACCTTCCACCGCCAGCTTCGCTCAAAAAACT
CCTTTTCTTCGCAACTAGATGGCATTGAAGGACTGGGGCCTAAACGCAAGCAAAATCTGATGCGACATTTTAAATCTTTG
GCCAATATCAAGAAAGCTAGTGTTGATGAAATTGTCGAAGTGGGTGTACCGCGAAAAGTGGCAGAGGCAGTGCAGAGAAA
ATTGAGAGAGTCTAGAGATAAAAAAGAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(197-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

Helix-hairpin-helix domain (HHH_5)

(538-590)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

89.286

98.658

0.881
  uvrC Streptococcus pneumoniae D39

89.286

98.658

0.881
  uvrC Streptococcus pneumoniae TIGR4

89.286

98.658

0.881