Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   PUW62_RS07455 Genome accession   NZ_CP118046
Coordinates   1491173..1492963 (-) Length   596 a.a.
NCBI ID   WP_164232022.1    Uniprot ID   -
Organism   Streptococcus anginosus strain VSI52     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1486173..1497963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW62_RS07425 (PUW62_07425) - 1486964..1487416 (-) 453 WP_006268509.1 MarR family transcriptional regulator -
  PUW62_RS07430 (PUW62_07430) - 1487518..1488102 (-) 585 WP_024053010.1 uracil-DNA glycosylase family protein -
  PUW62_RS07440 (PUW62_07440) - 1488112..1488969 (-) 858 Protein_1431 SDR family oxidoreductase -
  PUW62_RS07445 (PUW62_07445) pepV 1489025..1490425 (-) 1401 WP_070584413.1 dipeptidase PepV -
  PUW62_RS07450 (PUW62_07450) - 1490445..1491050 (-) 606 WP_274996913.1 nitroreductase family protein -
  PUW62_RS07455 (PUW62_07455) uvrC 1491173..1492963 (-) 1791 WP_164232022.1 excinuclease ABC subunit UvrC Machinery gene
  PUW62_RS07460 (PUW62_07460) ptsP 1493114..1494847 (-) 1734 WP_070812485.1 phosphoenolpyruvate--protein phosphotransferase -
  PUW62_RS07465 (PUW62_07465) - 1494849..1495112 (-) 264 WP_003023815.1 phosphocarrier protein HPr -
  PUW62_RS07470 (PUW62_07470) nrdH 1495510..1495728 (+) 219 WP_003023812.1 glutaredoxin-like protein NrdH -

Sequence

Protein


Download         Length: 596 a.a.        Molecular weight: 68680.21 Da        Isoelectric Point: 9.5420

>NTDB_id=720690 PUW62_RS07455 WP_164232022.1 1491173..1492963(-) (uvrC) [Streptococcus anginosus strain VSI52]
MNNLIKSKLELLPTSPGCYIHKDKNGIIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIEDFEFIVTESNIEALLLEIN
LIKENRPKYNIMLKDDKSYPFIKITNEIYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPEKVCF
YYHIGQCRAHTVCHNDPHFFQEMTQEVADFLKGHDNKIIDELKGKMTSAAENMEFEKAAEYRNLLQSIATLRTKQRVIAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNMFPYYNDPDEDFLTYIGQFYQEKSHLIPNEILIPSDIDEIAVQAV
VDTKILKPQRGEKKQLVNLAIKNAQVSLQQKFDLLEKSVEKTQGAIENLGQLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FINGKPSKKDYRKYKIKTVIGPDDYASMREVIKRRYSRVMRDGLIPPDLIVIDGGQGQVNIAKDVIQNQLGLDIPIAGLQ
KNDKHQTHELLFGDPLKVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMRHFKSL
ANIKKASVDEIVEVGVPRKVAEAVQRKLRESRDKKE

Nucleotide


Download         Length: 1791 bp        

>NTDB_id=720690 PUW62_RS07455 WP_164232022.1 1491173..1492963(-) (uvrC) [Streptococcus anginosus strain VSI52]
ATGAACAACTTGATTAAATCAAAATTAGAATTGTTGCCTACTAGTCCAGGTTGCTATATTCATAAAGATAAAAATGGCAT
TATCATCTATGTTGGAAAAGCTAAGAATCTGCGTAATCGGGTGCGCTCTTATTTTCGTGGGAGCCATGATACTAAAACGG
AAGCACTGGTGTCTGAGATTGAGGATTTTGAGTTTATTGTCACGGAGTCTAATATTGAAGCCTTGCTGCTTGAAATCAAT
CTAATCAAGGAAAATCGGCCTAAATATAACATCATGCTTAAGGACGATAAGTCCTACCCTTTTATCAAAATCACCAATGA
GATATATCCGCGACTTATTATTACACGTCAGGTTAAAAAAGATGGTGGTTTATATTTTGGCCCGTATCCTGATGTAGGTG
CTGCGAATGAAATTAAGCGCCTGCTGGATCGCATTTTTCCTTTCCGCAAGTGTACCAATCCACCTGAGAAAGTTTGCTTC
TACTATCATATCGGACAGTGTCGAGCTCATACTGTCTGCCATAATGATCCACATTTCTTTCAAGAGATGACTCAAGAAGT
AGCAGATTTCCTCAAAGGTCATGATAATAAGATTATTGATGAATTGAAAGGAAAAATGACTAGTGCTGCTGAAAATATGG
AATTTGAAAAAGCGGCTGAATACCGAAATTTGCTTCAAAGTATTGCGACACTTCGCACCAAGCAACGAGTGATAGCAAAG
GATTTACAGAATCGGGATGTCTTTGGCTATTATGTGGACAAAGGATGGATGTGTGTACAGGTTTTCTTTGTCCGTCAAGG
AAAACTCATTGAGCGAGATGTAAATATGTTTCCTTATTACAATGACCCTGACGAGGATTTTCTGACCTATATTGGTCAAT
TTTATCAGGAAAAATCTCATCTGATTCCCAATGAAATTTTGATTCCATCTGATATTGATGAAATAGCTGTTCAGGCTGTG
GTGGATACGAAGATTCTCAAACCTCAGCGAGGAGAGAAGAAACAGCTGGTTAATTTGGCTATTAAAAATGCGCAAGTTAG
TTTGCAGCAGAAGTTTGATTTGTTGGAGAAATCTGTTGAAAAAACACAGGGAGCTATTGAAAATCTAGGTCAGTTGCTCA
ATATTCCCACTCCAGTTCGGATTGAATCGTTTGATAATTCCAATATTATGGGAACAAGTCCTGTTTCAGCTATGGTGGTT
TTTATCAATGGCAAACCCAGCAAAAAAGATTATCGCAAGTATAAGATTAAGACAGTTATCGGTCCTGATGACTATGCTAG
TATGCGAGAAGTGATTAAGCGCCGTTACAGTCGGGTTATGCGAGATGGTTTAATACCGCCTGATCTTATTGTCATTGACG
GTGGTCAGGGTCAAGTCAATATTGCTAAAGACGTCATTCAAAATCAATTAGGGTTAGATATTCCTATCGCTGGTTTGCAA
AAAAATGACAAGCACCAGACGCATGAATTGCTCTTTGGCGATCCTTTGAAAGTGGTTGAGTTATCTCGCAATTCGCAGGA
ATTTTTCCTCTTACAACGCATTCAAGATGAGGTGCACCGCTTTGCCATTACCTTCCACCGCCAGCTTCGCTCAAAAAACT
CCTTTTCTTCGCAACTAGATGGCATTGAAGGACTGGGGCCTAAACGCAAGCAAAATCTGATGCGACATTTTAAATCTTTG
GCCAATATCAAGAAAGCTAGTGTTGATGAAATTGTCGAAGTGGGTGTACCGCGAAAAGTGGCAGAGGCAGTGCAGAGAAA
ATTGAGAGAGTCTAGAGATAAAAAAGAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(197-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

Helix-hairpin-helix domain (HHH_5)

(538-590)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

89.116

98.658

0.879
  uvrC Streptococcus pneumoniae D39

89.116

98.658

0.879
  uvrC Streptococcus pneumoniae TIGR4

89.116

98.658

0.879