Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   NW973_RS04645 Genome accession   NZ_CP102961
Coordinates   970455..971024 (-) Length   189 a.a.
NCBI ID   WP_031867118.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 03-RR-88     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 965455..976024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW973_RS04620 (NW973_04620) istB 966221..966982 (-) 762 WP_001066123.1 IS21-like element helper ATPase IstB -
  NW973_RS04625 (NW973_04625) istA 966975..968267 (-) 1293 WP_029550026.1 IS21 family transposase -
  NW973_RS04630 (NW973_04630) - 968475..970121 (+) 1647 WP_040968626.1 IS1182 family transposase -
  NW973_RS04645 (NW973_04645) comK/comK1 970455..971024 (-) 570 WP_031867118.1 competence protein ComK Regulator
  NW973_RS04650 (NW973_04650) - 971234..971452 (+) 219 WP_000876826.1 IDEAL domain-containing protein -
  NW973_RS04655 (NW973_04655) - 971533..972519 (-) 987 WP_000668818.1 lipoate--protein ligase -
  NW973_RS04660 (NW973_04660) - 972718..972894 (+) 177 WP_000214898.1 YkvS family protein -
  NW973_RS04665 (NW973_04665) - 972909..973511 (+) 603 WP_001033865.1 CPBP family glutamic-type intramembrane protease -
  NW973_RS13855 - 973826..973888 (+) 63 WP_231561937.1 putative holin-like toxin -
  NW973_RS04670 (NW973_04670) - 974526..974810 (+) 285 WP_258410543.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22629.88 Da        Isoelectric Point: 9.6091

>NTDB_id=720574 NW973_RS04645 WP_031867118.1 970455..971024(-) (comK/comK1) [Staphylococcus aureus strain 03-RR-88]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEVLTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=720574 NW973_RS04645 WP_031867118.1 970455..971024(-) (comK/comK1) [Staphylococcus aureus strain 03-RR-88]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCTATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGTATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterProScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

99.471

100

0.995
  comK/comK1 Staphylococcus aureus N315

99.471

100

0.995