Detailed information NTG0720474

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW969_RS09085
• Genome accession: NZ_CP102958
• Coordinates: 1890805..1891848 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 15-G-54
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1885805..1896848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW969_RS09055 (NW969_09055)	-	1886226..1887482 (-)	1257	WP_001793428.1	aminopeptidase	-
NW969_RS09060 (NW969_09060)	-	1887485..1887685 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW969_RS09065 (NW969_09065)	-	1887832..1888296 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW969_RS09070 (NW969_09070)	-	1888303..1888578 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW969_RS09075 (NW969_09075)	-	1888856..1890073 (+)	1218	WP_045158466.1	YihY/virulence factor BrkB family protein	-
NW969_RS09080 (NW969_09080)	vraR	1890186..1890815 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
NW969_RS09085 (NW969_09085)	vraS	1890805..1891848 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW969_RS09090 (NW969_09090)	liaF	1891845..1892546 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
NW969_RS09095 (NW969_09095)	-	1892561..1892947 (-)	387	WP_001110179.1	hypothetical protein	-
NW969_RS09100 (NW969_09100)	map	1893164..1893922 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW969_RS09105 (NW969_09105)	-	1894449..1895435 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW969_RS09110 (NW969_09110)	-	1895624..1896037 (-)	414	WP_258412606.1	hypothetical protein	-
NW969_RS09115 (NW969_09115)	-	1896066..1896174 (-)	109	Protein_1755	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720474 NW969_RS09085 WP_001017131.1 1890805..1891848(-) (vraS) [Staphylococcus aureus strain 15-G-54]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720474 NW969_RS09085 WP_001017131.1 1890805..1891848(-) (vraS) [Staphylococcus aureus strain 15-G-54]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTACTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTGCAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1