Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NW959_RS09210 Genome accession   NZ_CP102957
Coordinates   1899559..1900188 (-) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain 18-H-62     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1894559..1905188
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW959_RS09180 (NW959_09180) - 1894980..1895510 (-) 531 WP_258472925.1 acyl-CoA thioesterase -
  NW959_RS09185 (NW959_09185) - 1895600..1896856 (-) 1257 WP_078103502.1 aminopeptidase -
  NW959_RS09190 (NW959_09190) - 1896859..1897059 (-) 201 WP_000180460.1 DUF1128 family protein -
  NW959_RS09195 (NW959_09195) - 1897206..1897670 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  NW959_RS09200 (NW959_09200) - 1897677..1897952 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  NW959_RS09205 (NW959_09205) - 1898230..1899447 (+) 1218 WP_179330255.1 YihY/virulence factor BrkB family protein -
  NW959_RS09210 (NW959_09210) vraR 1899559..1900188 (-) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  NW959_RS09215 (NW959_09215) vraS 1900178..1901221 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  NW959_RS09220 (NW959_09220) liaF 1901218..1901919 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  NW959_RS09225 (NW959_09225) - 1901934..1902320 (-) 387 WP_258414722.1 hypothetical protein -
  NW959_RS09230 (NW959_09230) map 1902537..1903295 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  NW959_RS09235 (NW959_09235) - 1903826..1904812 (+) 987 WP_000999713.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=720431 NW959_RS09210 WP_000153535.1 1899559..1900188(-) (vraR) [Staphylococcus aureus strain 18-H-62]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=720431 NW959_RS09210 WP_000153535.1 1899559..1900188(-) (vraR) [Staphylococcus aureus strain 18-H-62]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAGGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373