Detailed information NTG0720420

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: PUW70_RS09840
• Genome accession: NZ_CP118029
• Coordinates: 1912330..1914891 (-)
• Length: 853 a.a.
• NCBI ID: WP_274996034.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain VSI68
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1907330..1919891

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW70_RS09815 (PUW70_09815)	ruvA	1907446..1908036 (-)	591	WP_024053223.1	Holliday junction branch migration protein RuvA	Machinery gene
PUW70_RS09820 (PUW70_09820)	-	1908198..1908641 (+)	444	WP_024053224.1	helix-turn-helix transcriptional regulator	-
PUW70_RS09825 (PUW70_09825)	hexB	1909046..1910992 (-)	1947	WP_024053225.1	DNA mismatch repair endonuclease MutL	Machinery gene
PUW70_RS09830 (PUW70_09830)	-	1911246..1911686 (+)	441	WP_024053226.1	LytTR family DNA-binding domain-containing protein	-
PUW70_RS09835 (PUW70_09835)	-	1911683..1912141 (+)	459	WP_024053227.1	DUF3021 domain-containing protein	-
PUW70_RS09840 (PUW70_09840)	hexA	1912330..1914891 (-)	2562	WP_274996034.1	DNA mismatch repair protein MutS	Machinery gene
PUW70_RS09845 (PUW70_09845)	argR	1915260..1915700 (-)	441	WP_003027809.1	arginine repressor	-
PUW70_RS09850 (PUW70_09850)	argS	1915804..1917492 (+)	1689	WP_024053229.1	arginine--tRNA ligase	-
PUW70_RS09855 (PUW70_09855)	nrdI	1917547..1918002 (-)	456	WP_024053230.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
PUW70_RS09860 (PUW70_09860)	-	1918078..1918587 (-)	510	WP_024053231.1	hypothetical protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 96046.76 Da
• Isoelectric Point: 5.0391

>NTDB_id=720420 PUW70_RS09840 WP_274996034.1 1912330..1914891(-) (hexA) [Streptococcus anginosus strain VSI68]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDATNAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNI
VCGEIRNLRAREVVLGYELSEMERQVLETQMNLLLSQVETTFDDVQLLGKDLSPLERQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLIENARTGKKHGSLYWLMDETKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKGIDSPVLEDLIAKLDEIPELASLIQSAISP
DAPNVITEGNIIKTGFDETLDKYRVVIRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTMATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIVVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMIEMIEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRADQILTRLESQVNEKPSFGIFNTL
PADAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=720420 PUW70_RS09840 WP_274996034.1 1912330..1914891(-) (hexA) [Streptococcus anginosus strain VSI68]
ATGACAAAAGAAAAACTATCTCCAGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGTTGTT
TCGCATGGGAGATTTTTATGAATTATTCTATGATGATGCGACCAATGCGGCACAGATTTTAGAGATTGCTCTGACTAGTC
GCAATAAAAACTCGGAAAATCCAATCCCAATGGCAGGAGTTCCTTACCATTCAGTGCAGCAATACATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGACTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATA
GTCTGTGGAGAAATCCGAAACCTGCGAGCGCGTGAAGTGGTCTTAGGGTATGAATTGTCTGAAATGGAGCGCCAAGTATT
GGAGACTCAAATGAATCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCGC
CGCTAGAGCGCCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGACTACTCAACTATGGCAAGTCTGGATTTAATAGAGAATGCTCG
AACAGGAAAGAAGCACGGGAGCCTTTATTGGCTGATGGATGAGACTAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGGATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAGCGCAGTGACTTATCAGACAGTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCGAAAGATCTATTACAACTTGCTGCGACATTGAGTCATGTGCCACAAATTAAGGGAATTTTAAAAGGAATTGATA
GCCCAGTTTTGGAAGATTTGATTGCAAAATTGGATGAAATTCCTGAACTGGCGTCCTTAATTCAGTCAGCAATTTCGCCG
GATGCTCCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGATAAATATCGAGTGGTTAT
ACGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCTAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACAAATTCCCAGCTTGAACACGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTCTGAAAAATTCAGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGGGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAATATATCAAACGCCTGCAATCCTTGGCGC
AAACTATGGCAACAGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCTGAAAAGCAACACTTTGTGAGACCAGAATTTATT
GAGCAGCGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAGCTAATTACAGGCCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCGATTGTTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCTGAAAGCGCTCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGATTGAAATGATAGAAGCGAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTCATTCTTTTTGATGAGTTAGGAAGAGGAACAGCCACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCGGACAGGAGCTAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGGATCAAATATTGACACGATTAGAAAGCCAAGTAAATGAGAAGCCATCTTTTGGCATCTTTAATACATTA
CCTGCGGATGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (255-546)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.671	100	0.767
mutS	Pseudomonas stutzeri strain ATCC 17587	36.227	100	0.367