Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   NW959_RS02465 Genome accession   NZ_CP102957
Coordinates   527297..527866 (+) Length   189 a.a.
NCBI ID   WP_258415799.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 18-H-62     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 522297..532866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW959_RS02440 (NW959_02440) cysE 523510..524157 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  NW959_RS02445 (NW959_02445) cysS 524141..525541 (+) 1401 WP_000631966.1 cysteine--tRNA ligase -
  NW959_RS02450 (NW959_02450) - 525534..525938 (+) 405 WP_000370185.1 Mini-ribonuclease 3 -
  NW959_RS02455 (NW959_02455) rlmB 525946..526692 (+) 747 WP_000390329.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  NW959_RS02460 (NW959_02460) - 526692..527216 (+) 525 WP_000664732.1 NYN domain-containing protein -
  NW959_RS02465 (NW959_02465) sigH 527297..527866 (+) 570 WP_258415799.1 RNA polymerase sigma factor Regulator
  NW959_RS02470 (NW959_02470) rpmG 527981..528124 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  NW959_RS02475 (NW959_02475) secE 528180..528362 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  NW959_RS02480 (NW959_02480) nusG 528375..528923 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  NW959_RS02485 (NW959_02485) rplK 529104..529526 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  NW959_RS02490 (NW959_02490) rplA 529734..530426 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  NW959_RS02495 (NW959_02495) rplJ 530698..531198 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  NW959_RS02500 (NW959_02500) rplL 531241..531609 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  NW959_RS02505 (NW959_02505) - 531784..532392 (+) 609 WP_006189707.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23096.93 Da        Isoelectric Point: 9.6072

>NTDB_id=720403 NW959_RS02465 WP_258415799.1 527297..527866(+) (sigH) [Staphylococcus aureus strain 18-H-62]
MKYDLTTQDSTIKRNNAINDKDFEKLVMNLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNQLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=720403 NW959_RS02465 WP_258415799.1 527297..527866(+) (sigH) [Staphylococcus aureus strain 18-H-62]
TTGAAATATGATTTGACAACGCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGAATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATCAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974