Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   PUW70_RS02280 Genome accession   NZ_CP118029
Coordinates   435394..436026 (+) Length   210 a.a.
NCBI ID   WP_024052105.1    Uniprot ID   A0A413KQW8
Organism   Streptococcus anginosus strain VSI68     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 430394..441026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW70_RS02260 (PUW70_02260) - 430830..431570 (+) 741 WP_022526377.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  PUW70_RS02265 (PUW70_02265) stkP 431567..433441 (+) 1875 WP_024052108.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  PUW70_RS02270 (PUW70_02270) liaF 433702..434400 (+) 699 WP_024052107.1 cell wall-active antibiotics response protein LiaF -
  PUW70_RS02275 (PUW70_02275) - 434397..435392 (+) 996 WP_024052106.1 sensor histidine kinase -
  PUW70_RS02280 (PUW70_02280) vraR 435394..436026 (+) 633 WP_024052105.1 response regulator transcription factor Regulator
  PUW70_RS02285 (PUW70_02285) - 436066..437466 (+) 1401 WP_070241554.1 Cof-type HAD-IIB family hydrolase -
  PUW70_RS02290 (PUW70_02290) - 437468..437839 (+) 372 WP_024052103.1 S1 RNA-binding domain-containing protein -
  PUW70_RS02295 (PUW70_02295) - 437973..438290 (-) 318 WP_024052102.1 DUF960 domain-containing protein -
  PUW70_RS02300 (PUW70_02300) - 438410..438943 (-) 534 WP_024052101.1 DUF402 domain-containing protein -
  PUW70_RS02305 (PUW70_02305) recX 439021..439806 (-) 786 WP_042754014.1 recombination regulator RecX -
  PUW70_RS02310 (PUW70_02310) - 439870..440646 (-) 777 WP_024052099.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23718.25 Da        Isoelectric Point: 4.6571

>NTDB_id=720347 PUW70_RS02280 WP_024052105.1 435394..436026(+) (vraR) [Streptococcus anginosus strain VSI68]
MQILLVDDHEMVRLGLKGYLDLQDDVDVVAEASNGREGVERALELRPDVIMMDIVMPEMSGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=720347 PUW70_RS02280 WP_024052105.1 435394..436026(+) (vraR) [Streptococcus anginosus strain VSI68]
ATGCAGATTTTATTAGTAGATGACCATGAAATGGTAAGACTTGGCTTAAAAGGTTATTTGGATTTACAAGACGATGTGGA
TGTAGTGGCAGAAGCTTCAAATGGTCGCGAAGGAGTTGAAAGAGCTTTGGAGTTGCGTCCAGATGTGATTATGATGGACA
TTGTCATGCCTGAAATGAGTGGGATTGAAGCGACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTCATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCGGTTTTAGATGCGGGTGCTAAAGGATATATGCTCAAAACTTCTAGCGC
GGATGATATTTTACGAGCGGTCCGAAAAGTAGCCAAGGGTGAACTTGCTATTGAAACAGAAGTCAGCCAAAAAGTAGAAT
ATCATCGAAATCATATTGAATTGCACGAAGATTTGACTGCGCGTGAGCGAGATATTTTAGGACTACTGGCAAAAGGTTAT
GAAAATCAACGCATAGCAGATGAATTATTTATTTCTTTAAAGACAGTGAAAACACATGTGTCCAATATCTTATCAAAGCT
AGAAGTGAGCGATCGTACACAAGCTGTTGTTTATGCTTTCCAACATCACCTTGTCCCACAAGATGACATTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A413KQW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414