Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PT280_RS12685 Genome accession   NZ_CP118014
Coordinates   2596480..2597136 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain B-766     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2591480..2602136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PT280_RS12655 dcyD 2592360..2593346 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  PT280_RS12660 tcyL 2593361..2594029 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PT280_RS12665 tcyN 2594026..2594778 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PT280_RS12670 sdiA 2595008..2595730 (+) 723 WP_001154279.1 transcriptional regulator SdiA -
  PT280_RS12675 yecF 2595797..2596021 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PT280_RS12680 yecU 2596008..2596184 (-) 177 WP_000590347.1 protein YecU -
  PT280_RS25545 - 2596267..2596338 (-) 72 Protein_2445 transcriptional regulator -
  PT280_RS12685 letA 2596480..2597136 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PT280_RS12690 uvrC 2597133..2598965 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PT280_RS12695 pgsA 2599022..2599570 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PT280_RS12715 yecA 2600219..2600884 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=720289 PT280_RS12685 WP_000611335.1 2596480..2597136(+) (letA) [Escherichia coli strain B-766]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=720289 PT280_RS12685 WP_000611335.1 2596480..2597136(+) (letA) [Escherichia coli strain B-766]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486