Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW338_RS10340 Genome accession   NZ_CP102945
Coordinates   2066885..2067601 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain SCAID OTT1-2022 (150)     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2061885..2072601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW338_RS10305 (NW338_10305) - 2062331..2063422 (-) 1092 WP_000172942.1 replication initiation factor domain-containing protein -
  NW338_RS10310 (NW338_10310) - 2063597..2063899 (-) 303 WP_000386891.1 hypothetical protein -
  NW338_RS10315 (NW338_10315) - 2063913..2064233 (-) 321 WP_000805732.1 DUF961 family protein -
  NW338_RS10320 (NW338_10320) - 2064384..2064668 (-) 285 WP_000134547.1 hypothetical protein -
  NW338_RS10325 (NW338_10325) - 2064842..2065405 (+) 564 WP_001105704.1 accessory gene regulator AgrB -
  NW338_RS10330 (NW338_10330) agrD 2065409..2065549 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  NW338_RS10335 (NW338_10335) agrC 2065574..2066866 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  NW338_RS10340 (NW338_10340) agrA 2066885..2067601 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  NW338_RS10345 (NW338_10345) - 2067673..2067782 (+) 110 Protein_2001 hypothetical protein -
  NW338_RS10350 (NW338_10350) - 2067970..2068929 (-) 960 WP_001253293.1 carbohydrate kinase -
  NW338_RS10355 (NW338_10355) - 2068926..2070410 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  NW338_RS10360 (NW338_10360) - 2070559..2071509 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=720094 NW338_RS10340 WP_000688498.1 2066885..2067601(+) (agrA) [Staphylococcus aureus strain SCAID OTT1-2022 (150)]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720094 NW338_RS10340 WP_000688498.1 2066885..2067601(+) (agrA) [Staphylococcus aureus strain SCAID OTT1-2022 (150)]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996