Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PT746_RS12735 Genome accession   NZ_CP117974
Coordinates   2752031..2752675 (-) Length   214 a.a.
NCBI ID   WP_003090351.1    Uniprot ID   A0A0H2ZC55
Organism   Pseudomonas aeruginosa strain B-3509     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2747031..2757675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PT746_RS12705 - 2747285..2747539 (-) 255 WP_023081358.1 Txe/YoeB family addiction module toxin -
  PT746_RS12710 yefM 2747536..2747787 (-) 252 WP_004350479.1 YoeB-YefM toxin-antitoxin system antitoxin YefM -
  PT746_RS12715 - 2748010..2749242 (-) 1233 Protein_2516 integrase arm-type DNA-binding domain-containing protein -
  PT746_RS12725 pgsA 2749610..2750170 (-) 561 WP_003090349.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PT746_RS12730 uvrC 2750204..2752030 (-) 1827 WP_003097551.1 excinuclease ABC subunit UvrC -
  PT746_RS12735 letA 2752031..2752675 (-) 645 WP_003090351.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PT746_RS12740 pqsH 2753017..2754165 (-) 1149 WP_003090354.1 2-heptyl-3-hydroxy-4(1H)-quinolone synthase -
  PT746_RS12745 - 2754783..2755811 (+) 1029 WP_003097554.1 AraC family transcriptional regulator -
  PT746_RS12750 - 2755827..2757041 (-) 1215 WP_004350046.1 MFS transporter -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23608.53 Da        Isoelectric Point: 6.1073

>NTDB_id=719989 PT746_RS12735 WP_003090351.1 2752031..2752675(-) (letA) [Pseudomonas aeruginosa strain B-3509]
MIKVLVVDDHDLVRTGITRMLADIEGLQVVGQADCGEDCLKLARELKPDVVLMDVKMPGIGGLEATRKLLRSQPDIKVVV
VTVCEEDPFPTRLMQAGAAGYMTKGAGLEEMVQAIRQVFAGQRYISPQIAQQLALKSFQPQQHDSPFDSLSEREIQIALM
IANCHKVQSISDKLCLSPKTVNTYRYRIFEKLSITSDVELALLAVRHGMVDAAS

Nucleotide


Download         Length: 645 bp        

>NTDB_id=719989 PT746_RS12735 WP_003090351.1 2752031..2752675(-) (letA) [Pseudomonas aeruginosa strain B-3509]
GTGATTAAGGTGCTGGTGGTCGACGACCACGATCTGGTACGCACCGGTATTACCCGCATGCTGGCCGACATCGAAGGCTT
GCAAGTGGTCGGCCAGGCCGACTGCGGTGAAGACTGTCTGAAACTGGCCCGCGAACTGAAGCCGGATGTCGTCCTGATGG
ACGTGAAGATGCCCGGTATCGGCGGCCTGGAGGCAACCCGCAAGCTGCTGCGCAGCCAGCCCGACATCAAGGTCGTGGTA
GTCACCGTCTGCGAAGAGGATCCGTTCCCCACCCGCCTCATGCAGGCCGGCGCCGCCGGCTACATGACCAAGGGCGCGGG
GCTGGAGGAAATGGTCCAGGCGATTCGCCAGGTCTTCGCCGGCCAGCGCTATATCAGCCCGCAGATCGCCCAGCAACTGG
CGCTGAAGTCCTTCCAGCCGCAGCAGCACGATTCCCCCTTCGATTCGCTGTCCGAGCGCGAGATCCAGATCGCCCTGATG
ATCGCCAACTGCCACAAGGTGCAGAGCATCTCCGACAAGCTGTGCCTGTCGCCGAAGACCGTGAATACCTATCGCTACCG
CATCTTCGAGAAGCTCTCGATCACCAGCGACGTGGAGCTGGCGCTGCTCGCCGTCCGCCACGGCATGGTCGATGCCGCCA
GCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZC55

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

54.502

98.598

0.537
  letA Legionella pneumophila strain ERS1305867

54.502

98.598

0.537