Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PT723_RS10755 Genome accession   NZ_CP117971
Coordinates   2245693..2246349 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain B-1109     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2240693..2251349
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PT723_RS10725 dcyD 2241572..2242558 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  PT723_RS10730 tcyL 2242573..2243241 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PT723_RS10735 tcyN 2243238..2243990 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PT723_RS10740 sdiA 2244220..2244942 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  PT723_RS10745 yecF 2245010..2245234 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PT723_RS10750 yecU 2245221..2245397 (-) 177 WP_000590344.1 protein YecU -
  PT723_RS24330 - 2245435..2245551 (-) 117 WP_001302039.1 hypothetical protein -
  PT723_RS10755 letA 2245693..2246349 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PT723_RS10760 uvrC 2246346..2248178 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PT723_RS10765 pgsA 2248235..2248783 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PT723_RS10785 yecA 2249433..2250098 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=719929 PT723_RS10755 WP_000611335.1 2245693..2246349(+) (letA) [Escherichia coli strain B-1109]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=719929 PT723_RS10755 WP_000611335.1 2245693..2246349(+) (letA) [Escherichia coli strain B-1109]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486