Detailed information NTG0071969

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EL263_RS09800
• Genome accession: NZ_AP018938
• Coordinates: 1825571..1826581 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain ATCC 49619
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1820571..1831581

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL263_RS09775 (SPAT_1853)	-	1821724..1822029 (-)	306	WP_000977370.1	hypothetical protein	-
EL263_RS09780 (SPAT_1854)	-	1822191..1822643 (+)	453	WP_000079148.1	universal stress protein	-
EL263_RS09785 (SPAT_1855)	-	1822678..1824066 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
EL263_RS09790 (SPAT_1856)	-	1824132..1825094 (+)	963	WP_001124777.1	asparaginase	-
EL263_RS11525 (SPAT_1857)	-	1825091..1825507 (-)	417	WP_061849636.1	hypothetical protein	-
EL263_RS09800 (SPAT_1858)	ccpA	1825571..1826581 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EL263_RS09805 (SPAT_1859)	-	1827006..1827605 (-)	600	WP_054387484.1	response regulator transcription factor	-
EL263_RS09810 (SPAT_1860)	-	1827607..1828704 (-)	1098	WP_114880769.1	sensor histidine kinase	-
EL263_RS09815 (SPAT_1861)	-	1828704..1829441 (-)	738	WP_000832916.1	ABC transporter permease	-
EL263_RS09820 (SPAT_1862)	-	1829443..1830327 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
EL263_RS09825 (SPAT_1863)	-	1830314..1830508 (-)	195	WP_000820189.1	hypothetical protein	-
EL263_RS11895	-	1830505..1830711 (-)	207	Protein_1843	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=71969 EL263_RS09800 WP_000990607.1 1825571..1826581(-) (ccpA) [Streptococcus pneumoniae strain ATCC 49619]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=71969 EL263_RS09800 WP_000990607.1 1825571..1826581(-) (ccpA) [Streptococcus pneumoniae strain ATCC 49619]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568