Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PT284_RS10075 Genome accession   NZ_CP117959
Coordinates   1875984..1876640 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain B-2207     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1870984..1881640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PT284_RS10045 yecA 1872235..1872900 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  PT284_RS10065 pgsA 1873550..1874098 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PT284_RS10070 uvrC 1874155..1875987 (-) 1833 WP_001283429.1 excinuclease ABC subunit UvrC Machinery gene
  PT284_RS10075 letA 1875984..1876640 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PT284_RS25510 - 1876782..1876853 (+) 72 Protein_1837 transcriptional regulator -
  PT284_RS10080 yecU 1876936..1877112 (+) 177 WP_001326718.1 protein YecU -
  PT284_RS10085 yecF 1877099..1877323 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PT284_RS10090 sdiA 1877390..1878112 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  PT284_RS10095 tcyN 1878342..1879094 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PT284_RS10100 tcyL 1879091..1879759 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PT284_RS10105 dcyD 1879774..1880760 (-) 987 WP_001128222.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=719653 PT284_RS10075 WP_000611335.1 1875984..1876640(-) (letA) [Escherichia coli strain B-2207]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=719653 PT284_RS10075 WP_000611335.1 1875984..1876640(-) (letA) [Escherichia coli strain B-2207]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486