Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EL263_RS07590 Genome accession   NZ_AP018938
Coordinates   1437070..1438302 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1432070..1443302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS07560 (SPAT_1440) - 1432257..1433225 (+) 969 WP_000081003.1 NAD(P)/FAD-dependent oxidoreductase -
  EL263_RS07565 (SPAT_1441) whiA 1433259..1434170 (-) 912 WP_000011276.1 DNA-binding protein WhiA -
  EL263_RS07570 (SPAT_1442) - 1434167..1435144 (-) 978 WP_001231086.1 YvcK family protein -
  EL263_RS07575 (SPAT_1443) rapZ 1435141..1436031 (-) 891 WP_000163033.1 RNase adapter RapZ -
  EL263_RS07580 (SPAT_1444) - 1436083..1436463 (-) 381 WP_001140412.1 RidA family protein -
  EL263_RS07585 (SPAT_1445) yihA 1436474..1437061 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EL263_RS07590 (SPAT_1446) clpX 1437070..1438302 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EL263_RS07595 (SPAT_1447) - 1438334..1438504 (-) 171 WP_000442275.1 hypothetical protein -
  EL263_RS07600 (SPAT_1448) - 1438504..1439010 (-) 507 WP_000162486.1 dihydrofolate reductase -
  EL263_RS07605 (SPAT_1449) - 1439140..1439658 (-) 519 WP_000229874.1 Dps family protein -
  EL263_RS07610 (SPAT_1450) lytC 1440154..1441659 (-) 1506 WP_114880840.1 choline binding-anchored murein hydrolase LytC -
  EL263_RS07615 (SPAT_1451) tpiA 1441698..1442456 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  EL263_RS07620 (SPAT_1452) - 1442554..1443231 (-) 678 WP_000221614.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=71949 EL263_RS07590 WP_000106346.1 1437070..1438302(-) (clpX) [Streptococcus pneumoniae strain ATCC 49619]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=71949 EL263_RS07590 WP_000106346.1 1437070..1438302(-) (clpX) [Streptococcus pneumoniae strain ATCC 49619]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAATAATAAGGCGATTGACGAAAACAGCTCATATATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment