Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL263_RS02050 Genome accession   NZ_AP018938
Coordinates   376836..377525 (+) Length   229 a.a.
NCBI ID   WP_000518016.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 371836..382525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS02025 (SPAT_0377) gpsB 371945..372274 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EL263_RS02035 (SPAT_0378) - 372760..373917 (+) 1158 WP_000711391.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  EL263_RS02040 (SPAT_0379) mapZ 373930..375324 (+) 1395 WP_000039276.1 cell division site-positioning protein MapZ -
  EL263_RS02045 (SPAT_0380) gndA 375400..376824 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  EL263_RS02050 (SPAT_0381) covR 376836..377525 (+) 690 WP_000518016.1 response regulator transcription factor Regulator
  EL263_RS02055 (SPAT_0382) cbpC 377623..378588 (+) 966 WP_000771105.1 choline-binding protein CbpC -
  EL263_RS02060 (SPAT_0383) cbpJ 378607..379605 (+) 999 WP_000771134.1 choline-binding protein CbpJ -
  EL263_RS02065 (SPAT_0384) - 379723..380955 (-) 1233 WP_000765664.1 MFS transporter -
  EL263_RS02070 (SPAT_0385) - 381114..381584 (-) 471 WP_001810352.1 lanthionine synthetase LanC family protein -
  EL263_RS02075 - 381484..381822 (-) 339 WP_001820155.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26932.24 Da        Isoelectric Point: 6.9836

>NTDB_id=71928 EL263_RS02050 WP_000518016.1 376836..377525(+) (covR) [Streptococcus pneumoniae strain ATCC 49619]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=71928 EL263_RS02050 WP_000518016.1 376836..377525(+) (covR) [Streptococcus pneumoniae strain ATCC 49619]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment