Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SA231_RS13345 Genome accession   NZ_AP024203
Coordinates   2695147..2695770 (-) Length   207 a.a.
NCBI ID   WP_001045134.1    Uniprot ID   -
Organism   Staphylococcus aureus strain SA23-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2690147..2700770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA231_RS13320 (SA231_25710) - 2690479..2691675 (-) 1197 WP_000238227.1 exonuclease SbcCD subunit D -
  SA231_RS13325 - 2691987..2692070 (-) 84 WP_031785438.1 hypothetical protein -
  SA231_RS13330 (SA231_25720) - 2692609..2692953 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  SA231_RS13335 (SA231_25730) - 2693022..2694146 (-) 1125 WP_000992509.1 DUF445 domain-containing protein -
  SA231_RS13340 (SA231_25740) - 2694325..2694789 (-) 465 WP_000375864.1 helix-turn-helix transcriptional regulator -
  SA231_RS13345 (SA231_25750) vraR 2695147..2695770 (-) 624 WP_001045134.1 response regulator transcription factor Regulator
  SA231_RS13350 (SA231_25760) - 2695792..2696904 (-) 1113 WP_000437967.1 GAF domain-containing sensor histidine kinase -
  SA231_RS13355 (SA231_25770) - 2697067..2697888 (+) 822 WP_000669377.1 RluA family pseudouridine synthase -
  SA231_RS13360 (SA231_25780) fumC 2698345..2699730 (-) 1386 WP_000116239.1 class II fumarate hydratase -
  SA231_RS13365 (SA231_25790) - 2699926..2700321 (-) 396 WP_000901019.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23933.61 Da        Isoelectric Point: 5.3565

>NTDB_id=71881 SA231_RS13345 WP_001045134.1 2695147..2695770(-) (vraR) [Staphylococcus aureus strain SA23-1]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPEIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNDEKMIHPKAQDVIETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=71881 SA231_RS13345 WP_001045134.1 2695147..2695770(-) (vraR) [Staphylococcus aureus strain SA23-1]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCGCATTATCCGGAAATTAAAGTATTA
GTATTAACAAGTTACGTTGATGATGAACATGTAATATCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACAATTAGGCGTGTCATGAACGACGAAAAAATGATACATCCAAAAGCACAAGATGTAA
TCGAAACAGTTAGTCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.097

100

0.401
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377

Multiple sequence alignment