Detailed information NTG0718764

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NWE21_RS07945
• Genome accession: NZ_CP102748
• Coordinates: 1590556..1591605 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain Transconjugant cSFJ45
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1585556..1596605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE21_RS07925 (NWE21_07935)	nadE	1585962..1586786 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
NWE21_RS07930 (NWE21_07940)	-	1588082..1588609 (-)	528	WP_012027591.1	VanZ family protein	-
NWE21_RS07935 (NWE21_07945)	rlmN	1588606..1589718 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NWE21_RS07940 (NWE21_07950)	-	1589727..1590368 (-)	642	WP_012027595.1	YutD family protein	-
NWE21_RS07945 (NWE21_07955)	sepM	1590556..1591605 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
NWE21_RS07950 (NWE21_07960)	coaD	1591592..1592080 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
NWE21_RS07955 (NWE21_07965)	rsmD	1592070..1592609 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NWE21_RS07960 (NWE21_07970)	-	1592917..1593639 (-)	723	WP_012027598.1	lipoprotein	-
NWE21_RS07965 (NWE21_07975)	-	1593696..1594082 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NWE21_RS07970 (NWE21_07980)	-	1594082..1594300 (-)	219	WP_004194736.1	YqgQ family protein	-
NWE21_RS07975 (NWE21_07985)	-	1594608..1595210 (-)	603	WP_012027601.1	response regulator transcription factor	-
NWE21_RS07980 (NWE21_07990)	-	1595207..1596301 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=718764 NWE21_RS07945 WP_012775295.1 1590556..1591605(-) (sepM) [Streptococcus suis strain Transconjugant cSFJ45]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=718764 NWE21_RS07945 WP_012775295.1 1590556..1591605(-) (sepM) [Streptococcus suis strain Transconjugant cSFJ45]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605