Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   NWE21_RS06440 Genome accession   NZ_CP102748
Coordinates   1295786..1297135 (-) Length   449 a.a.
NCBI ID   WP_012027301.1    Uniprot ID   -
Organism   Streptococcus suis strain Transconjugant cSFJ45     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1290786..1302135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE21_RS06420 (NWE21_06430) pbp2b 1290851..1292926 (-) 2076 WP_012775443.1 penicillin-binding protein PBP2B -
  NWE21_RS06425 (NWE21_06435) - 1293003..1293752 (-) 750 WP_012027298.1 ATP-binding cassette domain-containing protein -
  NWE21_RS06430 (NWE21_06440) - 1293915..1294457 (-) 543 WP_012027299.1 ATP-binding cassette domain-containing protein -
  NWE21_RS06435 (NWE21_06445) vicX 1294976..1295779 (-) 804 WP_012027300.1 MBL fold metallo-hydrolase Regulator
  NWE21_RS06440 (NWE21_06450) micB 1295786..1297135 (-) 1350 WP_012027301.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NWE21_RS06445 (NWE21_06455) micA 1297128..1297832 (-) 705 WP_004298854.1 response regulator YycF Regulator
  NWE21_RS06450 (NWE21_06460) - 1298026..1298787 (+) 762 WP_012027304.1 amino acid ABC transporter ATP-binding protein -
  NWE21_RS06455 (NWE21_06465) - 1298798..1299637 (+) 840 WP_012027305.1 transporter substrate-binding domain-containing protein -
  NWE21_RS06460 (NWE21_06470) - 1299652..1300350 (+) 699 WP_012028333.1 amino acid ABC transporter permease -
  NWE21_RS06465 (NWE21_06475) - 1300365..1301024 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51079.14 Da        Isoelectric Point: 4.4857

>NTDB_id=718759 NWE21_RS06440 WP_012027301.1 1295786..1297135(-) (micB) [Streptococcus suis strain Transconjugant cSFJ45]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYWDNKQIKQLNQKVNALIEGNYADLLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=718759 NWE21_RS06440 WP_012027301.1 1295786..1297135(-) (micB) [Streptococcus suis strain Transconjugant cSFJ45]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATTGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATCTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCTAATTCCCTCAATGATTTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACACGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCAACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTGGCGCCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGATCTCCTTAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTATAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.725

97.105

0.677
  vicK Streptococcus mutans UA159

70.72

89.755

0.635