Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NWE22_RS02735 Genome accession   NZ_CP102747
Coordinates   524836..525525 (+) Length   229 a.a.
NCBI ID   WP_239604567.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SFJ45     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 519836..530525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS02710 (NWE22_02710) - 520166..521509 (+) 1344 WP_239604562.1 DEAD/DEAH box helicase -
  NWE22_RS02715 (NWE22_02715) - 521528..521752 (+) 225 WP_239604563.1 DUF4059 family protein -
  NWE22_RS02720 (NWE22_02720) trxB 521765..522682 (+) 918 WP_239604564.1 thioredoxin-disulfide reductase -
  NWE22_RS02725 (NWE22_02725) - 522692..523231 (+) 540 WP_239604565.1 YceD family protein -
  NWE22_RS02730 (NWE22_02730) gndA 523327..524754 (+) 1428 WP_239604566.1 NADP-dependent phosphogluconate dehydrogenase -
  NWE22_RS02735 (NWE22_02735) covR 524836..525525 (+) 690 WP_239604567.1 winged helix-turn-helix domain-containing protein Regulator
  NWE22_RS02740 (NWE22_02740) - 525605..526732 (+) 1128 WP_239604568.1 AI-2E family transporter -
  NWE22_RS02745 (NWE22_02745) - 526938..528185 (+) 1248 WP_239604569.1 aminoacyltransferase -
  NWE22_RS02750 (NWE22_02750) - 528163..529410 (+) 1248 WP_239604570.1 aminoacyltransferase -
  NWE22_RS02755 (NWE22_02755) nrdR 529484..529975 (+) 492 WP_171988930.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26264.16 Da        Isoelectric Point: 5.4091

>NTDB_id=718686 NWE22_RS02735 WP_239604567.1 524836..525525(+) (covR) [Streptococcus parasuis strain SFJ45]
MAKKILIAGKERNLSHFVSMELQKKEYIVDYASTGKEALSLAHETDFDLVLMSFQLSDMSSKELAKELLAIKPATVMIVV
VEPTEVADHGEDVLTYAVFYVVKPFVISDLVEQISDIFRGRDFIETNCKQVHLHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDVPGQASYIRTVRGFGYTMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=718686 NWE22_RS02735 WP_239604567.1 524836..525525(+) (covR) [Streptococcus parasuis strain SFJ45]
ATGGCTAAGAAAATTTTGATTGCTGGGAAAGAGCGTAATCTTTCACATTTTGTTTCCATGGAACTTCAGAAGAAGGAGTA
TATCGTTGATTATGCTTCAACAGGGAAAGAAGCTTTATCACTAGCTCATGAGACAGACTTTGATTTGGTTTTGATGAGTT
TCCAATTATCCGATATGTCCAGCAAGGAGTTGGCTAAGGAGCTTCTTGCAATCAAACCTGCTACGGTGATGATTGTAGTT
GTCGAACCAACAGAAGTGGCTGACCATGGGGAAGATGTATTGACGTATGCGGTATTTTACGTTGTGAAGCCATTTGTTAT
TAGTGACTTGGTGGAACAAATTTCCGATATTTTCCGTGGTAGAGATTTTATTGAAACAAATTGTAAACAAGTTCATTTGC
ATGCGGCCTATCGAGATTTAAAAGTTGATTTTCAAAACCGAACGGTCACTCGGGGAGATGAGTTAATCAACTTGACACGG
CGAGAATATGATTTGCTGGCGACGTTGATGAATAGTCCGGAACCAGTTAGCCGAGAACAGCTTCTTGAACGGGTCTGGAA
GTATGAAGCGGCCTCTGAAACCAATGTTGTGGATGTCTATATCCGTTATCTTCGTGGAAAATTAGATGTTCCAGGACAGG
CTTCCTATATTCGGACGGTACGTGGTTTTGGCTATACCATGAGAGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.085

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.373

100

0.437