Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PTA50_RS09205 Genome accession   NZ_CP117714
Coordinates   1921373..1922029 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain PBS4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1916373..1927029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PTA50_RS09175 (PTA50_09175) dcyD 1917252..1918238 (+) 987 WP_001128242.1 D-cysteine desulfhydrase -
  PTA50_RS09180 (PTA50_09180) tcyL 1918253..1918921 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PTA50_RS09185 (PTA50_09185) tcyN 1918918..1919670 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PTA50_RS09190 (PTA50_09190) sdiA 1919900..1920622 (+) 723 WP_089586234.1 transcriptional regulator SdiA -
  PTA50_RS09195 (PTA50_09195) yecF 1920690..1920914 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PTA50_RS09200 (PTA50_09200) yecU 1920901..1921077 (-) 177 WP_001302050.1 protein YecU -
  PTA50_RS24950 - 1921115..1921231 (-) 117 WP_001302039.1 hypothetical protein -
  PTA50_RS09205 (PTA50_09205) letA 1921373..1922029 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PTA50_RS09210 (PTA50_09210) uvrC 1922026..1923858 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PTA50_RS09215 (PTA50_09215) pgsA 1923915..1924463 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PTA50_RS09235 (PTA50_09235) yecA 1925113..1925778 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=718614 PTA50_RS09205 WP_000611335.1 1921373..1922029(+) (letA) [Escherichia coli strain PBS4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=718614 PTA50_RS09205 WP_000611335.1 1921373..1922029(+) (letA) [Escherichia coli strain PBS4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486