Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   MOP79_RS00080 Genome accession   NZ_CP102583
Coordinates   10771..11460 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain D39Mega17545     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5771..16460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MOP79_RS00060 - 6728..7735 (-) 1008 WP_000562411.1 phosphomevalonate kinase -
  MOP79_RS00065 mvaD 7722..8675 (-) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  MOP79_RS00070 mvk 8657..9535 (-) 879 WP_000163321.1 mevalonate kinase -
  MOP79_RS00075 cbpC 9657..10673 (-) 1017 WP_000771103.1 choline-binding protein CbpC -
  MOP79_RS00080 covR 10771..11460 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  MOP79_RS00085 gndA 11472..12896 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  MOP79_RS00090 mapZ 12972..14366 (-) 1395 WP_000039255.1 mid-cell-anchored protein MapZ -
  MOP79_RS00095 - 14379..15536 (-) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  MOP79_RS00105 gpsB 16022..16351 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=717833 MOP79_RS00080 WP_000518011.1 10771..11460(-) (covR) [Streptococcus pneumoniae strain D39Mega17545]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=717833 MOP79_RS00080 WP_000518011.1 10771..11460(-) (covR) [Streptococcus pneumoniae strain D39Mega17545]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467