Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL277_RS01945 Genome accession   NZ_AP018936
Coordinates   362453..363142 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NU83127     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 357453..368142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL277_RS01920 (SPNU_0359) gpsB 357562..357891 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EL277_RS01930 (SPNU_0360) - 358377..359534 (+) 1158 WP_000711388.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  EL277_RS01935 (SPNU_0361) mapZ 359547..360941 (+) 1395 WP_000039291.1 cell division site-positioning protein MapZ -
  EL277_RS01940 (SPNU_0362) gndA 361017..362441 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  EL277_RS01945 (SPNU_0363) covR 362453..363142 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  EL277_RS01950 (SPNU_0364) cbpC 363241..364263 (+) 1023 WP_000771084.1 choline-binding protein CbpC -
  EL277_RS01955 (SPNU_0365) cbpJ 364281..365279 (+) 999 WP_000698047.1 choline-binding protein CbpJ -
  EL277_RS01960 (SPNU_0366) - 365397..366629 (-) 1233 WP_000765691.1 MFS transporter -
  EL277_RS01965 (SPNU_0367) - 366672..367547 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=71775 EL277_RS01945 WP_000518018.1 362453..363142(+) (covR) [Streptococcus pneumoniae strain NU83127]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=71775 EL277_RS01945 WP_000518018.1 362453..363142(+) (covR) [Streptococcus pneumoniae strain NU83127]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment