Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   MGCS35957_RS02725 Genome accession   NZ_CP117288
Coordinates   517061..518017 (+) Length   318 a.a.
NCBI ID   WP_046166194.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 512061..523017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS35957_RS02710 (MGCS35957_01110) comE/blpR 514607..515356 (+) 750 WP_030126108.1 response regulator transcription factor Regulator
  MGCS35957_RS02720 (MGCS35957_01114) - 515698..516831 (-) 1134 WP_275902597.1 ISAs1-like element IS1548 family transposase -
  MGCS35957_RS02725 (MGCS35957_01116) comD/blpH 517061..518017 (+) 957 WP_046166194.1 GHKL domain-containing protein Regulator
  MGCS35957_RS02730 (MGCS35957_01118) - 518165..518290 (-) 126 WP_011017462.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  MGCS35957_RS02735 (MGCS35957_01122) - 518367..519731 (-) 1365 WP_084916305.1 bacteriocin secretion accessory protein -
  MGCS35957_RS02740 (MGCS35957_01124) comA/nlmT 519742..521895 (-) 2154 WP_084916306.1 peptide cleavage/export ABC transporter Regulator
  MGCS35957_RS02745 (MGCS35957_01126) - 522182..522409 (+) 228 WP_002992018.1 Blp family class II bacteriocin -
  MGCS35957_RS02750 (MGCS35957_01128) - 522422..522622 (+) 201 WP_003060803.1 class IIb bacteriocin, lactobin A/cerein 7B family -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 36680.03 Da        Isoelectric Point: 8.2412

>NTDB_id=717698 MGCS35957_RS02725 WP_046166194.1 517061..518017(+) (comD/blpH) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957]
MIFSIVAGTMVLLLIQAFNYDFSHLRKKKLNQRTRTIISIANFSMILYFITIPMIDFIEEVENINFTHYQEMITAIYFLL
FICFVNLLDRNLRQELQKQVVLQKELQLQNMARYSKQIEGLYQNIRSFRHDYANILTSLKIGIDCKDIEMISSIYHKVLK
DSGKVLRGEKFNLARLRNINDLPLKSLLFVKLSEAQRLSIPVSIEIGEPISIKNIELIDFLTLVSILIDNAIEGAAESGI
VLCFFEQFGKQILIVQNDTFEKQINLSTIFERGVSSKGNNRGVGLSNVREILESYPTVTLKTVSNHFVFKQILEIEIL

Nucleotide


Download         Length: 957 bp        

>NTDB_id=717698 MGCS35957_RS02725 WP_046166194.1 517061..518017(+) (comD/blpH) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957]
ATGATTTTTTCTATTGTTGCTGGTACTATGGTTTTGCTGCTGATTCAAGCTTTTAATTATGACTTTAGTCATTTAAGAAA
AAAGAAACTAAATCAACGTACTAGAACGATTATATCTATTGCCAACTTTAGCATGATATTGTACTTTATTACCATTCCAA
TGATAGATTTTATCGAAGAAGTTGAAAATATTAATTTTACGCACTATCAAGAGATGATAACAGCAATTTATTTTCTTTTA
TTTATTTGTTTTGTAAATTTATTGGATCGGAACTTACGCCAAGAATTACAAAAGCAAGTTGTTCTACAAAAAGAGTTACA
ATTACAGAATATGGCTCGCTATAGTAAGCAAATCGAAGGACTGTATCAAAATATCAGAAGTTTTAGACATGATTATGCAA
ATATTTTAACAAGCTTGAAAATAGGCATTGATTGCAAAGATATTGAAATGATTTCAAGCATTTATCATAAGGTGTTGAAA
GATTCAGGGAAGGTTTTAAGGGGAGAAAAATTCAATCTAGCAAGGCTGAGAAATATAAACGACCTTCCTCTGAAAAGTTT
ACTGTTTGTAAAATTATCAGAAGCTCAACGCTTATCCATACCTGTATCTATAGAAATTGGGGAACCGATTTCTATAAAAA
ACATTGAGTTAATCGATTTTTTAACCCTTGTTTCTATCTTGATAGATAATGCAATCGAAGGTGCAGCAGAGTCGGGGATA
GTTCTTTGTTTTTTTGAACAATTTGGTAAACAGATATTAATTGTTCAAAATGATACTTTTGAAAAACAGATTAATCTTTC
CACGATTTTTGAGCGAGGTGTTTCTTCAAAAGGAAATAATAGGGGAGTTGGTTTATCAAATGTTAGGGAGATATTAGAAT
CATATCCCACTGTTACCCTCAAAACAGTAAGTAATCATTTTGTTTTTAAACAGATTCTAGAAATAGAAATCCTATAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(216-313)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

40.391

96.541

0.39