Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   PO908_RS09710 Genome accession   NZ_CP117042
Coordinates   1876390..1878336 (-) Length   648 a.a.
NCBI ID   WP_003026650.1    Uniprot ID   -
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1871390..1883336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS09685 (PO908_09650) cinA 1871762..1873033 (-) 1272 WP_021002200.1 competence/damage-inducible protein A Machinery gene
  PO908_RS09690 (PO908_09655) - 1873634..1874054 (+) 421 Protein_1864 EamA family transporter -
  PO908_RS09695 (PO908_09660) - 1874157..1874735 (-) 579 WP_021002201.1 DNA-3-methyladenine glycosylase I -
  PO908_RS09700 (PO908_09665) ruvA 1874746..1875336 (-) 591 WP_021002202.1 Holliday junction branch migration protein RuvA Machinery gene
  PO908_RS09705 (PO908_09670) - 1875498..1876007 (+) 510 WP_003026648.1 helix-turn-helix domain-containing protein -
  PO908_RS09710 (PO908_09675) hexB 1876390..1878336 (-) 1947 WP_003026650.1 DNA mismatch repair endonuclease MutL Machinery gene
  PO908_RS09715 (PO908_09680) brsR 1878581..1879021 (+) 441 WP_041784066.1 LytTR family DNA-binding domain-containing protein Regulator
  PO908_RS09720 (PO908_09685) - 1879018..1879476 (+) 459 WP_021002204.1 DUF3021 domain-containing protein -
  PO908_RS09725 (PO908_09690) hexA 1879665..1882226 (-) 2562 WP_394467977.1 DNA mismatch repair protein MutS Machinery gene
  PO908_RS09730 (PO908_09695) argR 1882389..1882829 (-) 441 WP_003027809.1 arginine repressor -

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73161.36 Da        Isoelectric Point: 5.1688

>NTDB_id=716471 PO908_RS09710 WP_003026650.1 1876390..1878336(-) (hexB) [Streptococcus anginosus strain CGMH_KH1]
MSKIIELPENLANQIAAGEVIERPSSVVKELIENSIDAGATQIIVEIEEAGLRSIQVIDNGEGIEHEEVSLALRRHATSK
IKKQADLFRIRTLGFRGEALPSIASVSRLTIETATSSGAHGTLLIAQGGEVETLEPSSCPRGTKIKVEDLFFNTPARLKY
MKSQQAELSHIVDVINRLSLAHPEVAFTLVNDGKEMTRTAGTGNLRQAIAGIYGLTTAKKMIEILASDLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIRIDPYLADVNVHPTKQEVRISKERELMVLISQ
AIAASLKEQDLIPDALENLAKSTINRAIKPEQTSLPLKENRLYYDKERNDFFVKPQVSEAQPSFEESARLDQQSADTDEL
NSKAASVKFAERQSPSYNQLDHPELDQASLERALDKLNGEETSTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVK
YEYYREKIGDVDASQQQLLVPYIFEFPADDMLRLKQRMTLLEEVGVFLEEYGTNQFILREHPIWLKEEEIESGIYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLIFQLSQCDNPYNCPHGRPVLVNFTKSDMGKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=716471 PO908_RS09710 WP_003026650.1 1876390..1878336(-) (hexB) [Streptococcus anginosus strain CGMH_KH1]
ATGTCAAAAATTATTGAACTACCAGAAAATCTTGCTAATCAGATTGCAGCAGGTGAGGTTATTGAGCGACCTAGCAGCGT
TGTCAAGGAGTTAATAGAAAATTCTATTGATGCTGGTGCCACTCAGATTATAGTTGAGATTGAAGAAGCGGGACTCAGGA
GCATTCAAGTCATTGATAATGGTGAAGGAATTGAGCATGAGGAGGTTTCCTTGGCTTTACGGCGGCATGCTACTAGTAAA
ATCAAGAAACAAGCCGACCTTTTTCGAATTCGGACATTGGGCTTTCGGGGCGAGGCACTTCCATCCATTGCCTCTGTTTC
ACGTTTGACGATTGAAACTGCGACAAGTAGTGGTGCACATGGAACGCTTCTGATTGCGCAAGGTGGAGAAGTTGAGACTT
TAGAGCCAAGTAGCTGTCCTAGGGGCACCAAAATCAAAGTGGAAGACCTTTTTTTCAACACGCCTGCTCGCTTGAAATAT
ATGAAAAGTCAACAAGCGGAACTATCTCACATTGTAGATGTGATTAACCGTTTGAGCTTGGCTCATCCGGAGGTCGCTTT
CACTCTTGTTAATGACGGTAAAGAGATGACACGGACAGCAGGAACAGGAAATCTGCGTCAAGCAATTGCTGGCATTTATG
GACTGACAACAGCCAAAAAAATGATTGAAATTTTAGCATCTGATTTGGATTTTGAAGTATCAGGCTATATTAGTTTGCCA
GAATTAACAAGGGCTAATCGGAATTACATTACTATCCTCATCAATGGTCGCTACATCAAGAATTTCCTACTCAATCGAGC
TATTTTAGATGGATATGGTAGCAAGCTCATGGTGGGACGTTTTCCGATTGCTGTGATTGATATTCGGATTGACCCATATC
TTGCTGATGTCAATGTTCACCCGACCAAGCAAGAAGTGCGGATTTCAAAGGAGCGAGAGCTCATGGTCTTGATATCGCAA
GCTATTGCTGCAAGTTTGAAAGAGCAAGATTTGATTCCGGACGCATTAGAGAATTTAGCCAAATCAACCATTAACCGAGC
AATTAAGCCTGAACAGACCAGCCTCCCTCTCAAAGAGAACCGACTTTATTACGATAAAGAAAGAAATGACTTCTTTGTGA
AACCACAAGTGTCAGAAGCTCAACCTTCTTTTGAGGAATCTGCCCGATTAGACCAACAATCTGCTGATACAGATGAACTC
AATTCAAAAGCTGCTTCTGTCAAATTTGCAGAAAGGCAATCTCCTTCTTACAATCAACTAGATCATCCAGAGCTGGATCA
GGCGAGCTTAGAGAGAGCTTTAGATAAGCTAAATGGAGAAGAAACTTCAACGTTTCCAGAATTGGAATATTTCGGGCAAA
TGCACGGCACCTACCTTTTTGCTCAAGGAAACGGTGGCCTTTATATTATTGACCAACATGCAGCTCAAGAGCGAGTAAAG
TACGAATATTACCGTGAAAAAATCGGAGATGTAGATGCTAGTCAGCAGCAGCTTCTGGTTCCCTATATCTTTGAATTTCC
AGCTGATGATATGTTGCGTCTGAAACAACGAATGACTCTTTTAGAAGAAGTCGGTGTTTTCCTTGAAGAATACGGAACTA
ATCAATTTATTCTTCGTGAACATCCCATTTGGCTTAAGGAAGAGGAGATCGAATCAGGTATTTATGAGATGTGCGATATG
CTGCTTCTAACCAAGGAAGTCTCTATCAAGAAATATCGCGCTGAGCTGGCTATTATGATGAGTTGCAAACGCTCTATTAA
AGCCAATCACAGTTTAGATGACTATTCAGCGCGTGATTTGATTTTTCAGTTATCACAATGCGACAATCCCTACAACTGCC
CTCACGGTCGTCCCGTTTTGGTCAACTTCACCAAATCTGATATGGGAAAAATGTTCCGTCGGATTCAGGAAAACCATACT
AGCCTGAGAGAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-116)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.042

100

0.772