Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   K6K39_RS34350 Genome accession   NZ_AP024135
Coordinates   7806669..7807325 (-) Length   218 a.a.
NCBI ID   WP_059248034.1    Uniprot ID   A0ABS9JI14
Organism   Streptomyces sp. EAS-AB2608 strain NBRC 114648     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7801669..7812325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6K39_RS34330 (EASAB2608_07026) - 7802499..7803260 (+) 762 WP_059248038.1 GntR family transcriptional regulator -
  K6K39_RS34335 (EASAB2608_07027) - 7803389..7804381 (+) 993 WP_059248037.1 L-threonylcarbamoyladenylate synthase -
  K6K39_RS34340 (EASAB2608_07028) - 7804475..7805116 (-) 642 WP_059248036.1 carbonic anhydrase -
  K6K39_RS34345 (EASAB2608_07029) - 7805414..7806571 (-) 1158 WP_059248035.1 ROK family protein -
  K6K39_RS34350 (EASAB2608_07030) vraR 7806669..7807325 (-) 657 WP_059248034.1 response regulator transcription factor Regulator
  K6K39_RS34355 (EASAB2608_07031) - 7807340..7808494 (-) 1155 WP_221335302.1 sensor histidine kinase -
  K6K39_RS34360 (EASAB2608_07032) - 7808602..7809522 (+) 921 WP_059248032.1 ATP-binding cassette domain-containing protein -
  K6K39_RS34365 (EASAB2608_07033) - 7809525..7810235 (+) 711 WP_221335303.1 ABC transporter permease -
  K6K39_RS34370 (EASAB2608_07034) - 7810362..7810805 (+) 444 WP_059248030.1 hypothetical protein -
  K6K39_RS34375 (EASAB2608_07035) mug 7810766..7811296 (-) 531 WP_079080886.1 G/U mismatch-specific DNA glycosylase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23519.22 Da        Isoelectric Point: 5.1979

>NTDB_id=71632 K6K39_RS34350 WP_059248034.1 7806669..7807325(-) (vraR) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRRLRPDVVAMDVRMPLMDGIEATRAVLRTVPEPPKI
LVVTTFEDDEYVYDALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRRLAARYGDGDRPARAALERARLTEREA
EVLRLMTRGLSNAEIAARLVVGAETVKSHVSAVLAKLGARDRTQAVIAAYESGFVEPG

Nucleotide


Download         Length: 657 bp        

>NTDB_id=71632 K6K39_RS34350 WP_059248034.1 7806669..7807325(-) (vraR) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
ATGCCGGTCACCGTACTCCTCGTCGACGACGAACCCCTGGTCCGCGCGGGTCTGCGGGCCGTGCTGGAGGCACAGCCCGA
CATCGAGGTGGTGGGCGAGGCGGCCGACGGCGCGGCGGTCATCCCGCTGGTCCGACGACTGCGGCCGGACGTGGTGGCCA
TGGACGTCCGGATGCCGCTGATGGACGGGATCGAGGCCACGCGCGCGGTGCTGCGCACGGTGCCGGAGCCGCCGAAGATC
CTCGTGGTGACCACGTTCGAGGACGACGAGTACGTGTACGACGCGCTGCGCGCGGGCGCCGACGGGTTCCTGCTGAAGCG
GGCCCGCCCGGCCGAGATCGTGCACGCGGTGCGGCTGGTCGCGGAGGGCGAGTCGCTGCTGTTCCCGGCCTCCGTACGGC
GTCTCGCCGCCCGGTACGGCGACGGTGACCGGCCGGCGCGGGCCGCGCTGGAGCGGGCCCGGCTGACCGAGCGGGAGGCG
GAGGTGCTGCGGCTGATGACGCGGGGGCTGTCGAACGCCGAGATCGCCGCCCGGCTGGTCGTGGGCGCGGAGACGGTGAA
GTCGCATGTGAGCGCCGTCCTGGCCAAGTTGGGCGCGCGCGACCGCACCCAGGCGGTGATCGCTGCCTATGAGTCGGGGT
TCGTGGAACCGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(155-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.13

99.083

0.417
  degU Bacillus subtilis subsp. subtilis str. 168

37.333

100

0.385

Multiple sequence alignment