Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL424_RS05430 Genome accession   NZ_CP117020
Coordinates   1038761..1039417 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MLI106K3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1033761..1044417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL424_RS05395 (NL424_005390) - 1034137..1034820 (-) 684 Protein_997 integrase arm-type DNA-binding domain-containing protein -
  NL424_RS05400 (NL424_005395) - 1034901..1035620 (+) 720 WP_255046424.1 hypothetical protein -
  NL424_RS05420 (NL424_005415) pgsA 1036327..1036875 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL424_RS05425 (NL424_005420) uvrC 1036932..1038764 (-) 1833 WP_001595863.1 excinuclease ABC subunit UvrC Machinery gene
  NL424_RS05430 (NL424_005425) letA 1038761..1039417 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL424_RS05435 (NL424_005430) yecU 1039713..1039889 (+) 177 WP_000590347.1 protein YecU -
  NL424_RS05440 (NL424_005435) yecF 1039876..1040100 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL424_RS05445 (NL424_005440) sdiA 1040167..1040889 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  NL424_RS05450 (NL424_005445) tcyN 1041119..1041871 (-) 753 WP_001273003.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL424_RS05455 (NL424_005450) tcyL 1041868..1042536 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  NL424_RS05460 (NL424_005455) dcyD 1042551..1043537 (-) 987 WP_001373912.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=716229 NL424_RS05430 WP_000611328.1 1038761..1039417(-) (letA) [Escherichia coli strain MLI106K3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=716229 NL424_RS05430 WP_000611328.1 1038761..1039417(-) (letA) [Escherichia coli strain MLI106K3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482