Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   K6K39_RS23610 Genome accession   NZ_AP024135
Coordinates   5263791..5264432 (-) Length   213 a.a.
NCBI ID   WP_086697805.1    Uniprot ID   A0ABP5NW44
Organism   Streptomyces sp. EAS-AB2608 strain NBRC 114648     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5258791..5269432
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6K39_RS23590 (EASAB2608_04831) atpD 5259303..5260739 (+) 1437 WP_059252613.1 F0F1 ATP synthase subunit beta -
  K6K39_RS23595 (EASAB2608_04832) - 5260850..5261224 (+) 375 WP_023546729.1 F0F1 ATP synthase subunit epsilon -
  K6K39_RS23600 (EASAB2608_04833) - 5261373..5261819 (+) 447 WP_059252614.1 DUF2550 domain-containing protein -
  K6K39_RS23605 (EASAB2608_04834) - 5261835..5263655 (-) 1821 WP_221334842.1 glycoside hydrolase family 18 chitinase -
  K6K39_RS23610 (EASAB2608_04835) vraR 5263791..5264432 (-) 642 WP_086697805.1 response regulator transcription factor Regulator
  K6K39_RS23615 (EASAB2608_04836) - 5264429..5265601 (-) 1173 WP_221334843.1 sensor histidine kinase -
  K6K39_RS23620 (EASAB2608_04837) - 5265756..5266352 (+) 597 WP_221334844.1 hypothetical protein -
  K6K39_RS23625 (EASAB2608_04838) - 5266349..5266852 (+) 504 WP_086697802.1 DinB family protein -
  K6K39_RS23630 (EASAB2608_04839) - 5266869..5267441 (-) 573 WP_221334845.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
  K6K39_RS23635 (EASAB2608_04840) - 5267455..5268204 (-) 750 WP_059252620.1 ABC transporter permease -
  K6K39_RS23640 (EASAB2608_04841) - 5268245..5269030 (-) 786 WP_221334846.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22712.25 Da        Isoelectric Point: 4.7573

>NTDB_id=71613 K6K39_RS23610 WP_086697805.1 5263791..5264432(-) (vraR) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
MIRVLVAEDQSAVRAGLVLILRSAPDIEVVGEAADGEQAVELARSLGPDIVLMDVQMPRLDGVSATRRIVAERLADVLVL
TTFDLDEYVFGALRAGAAGFLLKNTEARDLLEAVRTVARGEGIVAPAVTRRLIAEFAAAPARDADADPAVLEGLTRRERE
VLGCIGEGLSNAQIATRLDMAEGTVKTHVSRLLAKLELRSRVQAAVLARELGI

Nucleotide


Download         Length: 642 bp        

>NTDB_id=71613 K6K39_RS23610 WP_086697805.1 5263791..5264432(-) (vraR) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
ATGATCCGTGTCCTGGTCGCCGAGGACCAGTCCGCCGTCCGCGCCGGGCTCGTCCTGATCCTGCGCAGCGCGCCGGACAT
CGAGGTGGTCGGCGAGGCCGCGGACGGTGAACAGGCGGTCGAGCTGGCCCGCAGCCTCGGTCCGGACATCGTCCTGATGG
ACGTGCAGATGCCCCGCCTCGACGGGGTGTCGGCGACCCGGCGGATCGTCGCCGAGCGGCTCGCGGACGTGCTCGTGCTG
ACCACCTTCGACCTCGACGAGTACGTGTTCGGCGCGCTCCGGGCGGGCGCGGCCGGCTTTCTGCTGAAGAACACCGAGGC
GCGGGATCTGCTGGAGGCGGTGCGCACGGTGGCGCGCGGGGAGGGGATCGTCGCGCCGGCCGTGACCCGGCGGCTGATCG
CCGAGTTCGCGGCGGCGCCGGCCCGGGACGCGGACGCCGACCCGGCCGTGCTGGAGGGGCTCACCCGGCGGGAGCGGGAG
GTGCTGGGCTGTATCGGCGAGGGCCTGTCGAACGCCCAGATCGCGACCCGGCTGGACATGGCGGAGGGCACGGTGAAGAC
GCACGTCAGCCGGTTGCTGGCCAAGCTGGAACTGCGCAGCCGGGTGCAAGCGGCCGTGCTCGCCCGGGAGTTGGGGATCT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-208)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.627

98.122

0.408
  degU Bacillus subtilis subsp. subtilis str. 168

37.557

100

0.39

Multiple sequence alignment