Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL411_RS11130 Genome accession   NZ_CP117006
Coordinates   1983282..1983938 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MLI108K3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1978282..1988938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL411_RS11100 (NL411_011100) dcyD 1979161..1980147 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NL411_RS11105 (NL411_011105) tcyL 1980162..1980830 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NL411_RS11110 (NL411_011110) tcyN 1980827..1981579 (+) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL411_RS11115 (NL411_011115) sdiA 1981809..1982531 (+) 723 WP_016236716.1 transcriptional regulator SdiA -
  NL411_RS11120 (NL411_011120) yecF 1982599..1982823 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL411_RS11125 (NL411_011125) yecU 1982810..1982986 (-) 177 WP_032149425.1 protein YecU -
  NL411_RS11130 (NL411_011130) letA 1983282..1983938 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL411_RS11135 (NL411_011135) uvrC 1983935..1985767 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NL411_RS11140 (NL411_011140) pgsA 1985824..1986372 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL411_RS11160 (NL411_011160) yecA 1987021..1987686 (+) 666 WP_072617294.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=715848 NL411_RS11130 WP_000611335.1 1983282..1983938(+) (letA) [Escherichia coli strain MLI108K3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=715848 NL411_RS11130 WP_000611335.1 1983282..1983938(+) (letA) [Escherichia coli strain MLI108K3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATTATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486