Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PQP10_RS05570 Genome accession   NZ_CP116976
Coordinates   1121322..1121978 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CUVM53     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1116322..1126978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQP10_RS24220 - 1116895..1117371 (-) 477 Protein_1101 Arm DNA-binding domain-containing protein -
  PQP10_RS05540 (PQP10_05540) - 1117452..1118192 (+) 741 WP_272772442.1 hypothetical protein -
  PQP10_RS05560 (PQP10_05560) pgsA 1118888..1119436 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PQP10_RS05565 (PQP10_05565) uvrC 1119493..1121325 (-) 1833 WP_040063802.1 excinuclease ABC subunit UvrC Machinery gene
  PQP10_RS05570 (PQP10_05570) letA 1121322..1121978 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PQP10_RS05575 (PQP10_05575) yecU 1122274..1122450 (+) 177 WP_000590344.1 protein YecU -
  PQP10_RS05580 (PQP10_05580) yecF 1122437..1122661 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PQP10_RS05585 (PQP10_05585) sdiA 1122728..1123450 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  PQP10_RS05590 (PQP10_05590) tcyN 1123680..1124432 (-) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PQP10_RS05595 (PQP10_05595) tcyL 1124429..1125097 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PQP10_RS05600 (PQP10_05600) dcyD 1125112..1126098 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=715419 PQP10_RS05570 WP_000611328.1 1121322..1121978(-) (letA) [Escherichia coli strain CUVM53]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=715419 PQP10_RS05570 WP_000611328.1 1121322..1121978(-) (letA) [Escherichia coli strain CUVM53]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482