Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   M0P28_RS11780 Genome accession   NZ_CP116958
Coordinates   2312579..2314522 (-) Length   647 a.a.
NCBI ID   WP_117479524.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain WUSP074     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2307579..2319522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0P28_RS11740 (M0P28_11740) - 2308407..2309597 (-) 1191 WP_048790986.1 MFS transporter -
  M0P28_RS11745 (M0P28_11745) - 2309757..2309930 (-) 174 WP_048790985.1 hypothetical protein -
  M0P28_RS11750 (M0P28_11750) - 2309980..2310189 (-) 210 WP_231729899.1 hypothetical protein -
  M0P28_RS11755 (M0P28_11755) - 2310147..2310428 (-) 282 WP_003066911.1 hypothetical protein -
  M0P28_RS11760 (M0P28_11760) - 2310498..2310707 (-) 210 WP_003066913.1 hypothetical protein -
  M0P28_RS11765 (M0P28_11765) - 2310729..2310905 (-) 177 WP_003066916.1 hypothetical protein -
  M0P28_RS11770 (M0P28_11770) - 2311053..2311904 (+) 852 WP_003066919.1 helix-turn-helix domain-containing protein -
  M0P28_RS11775 (M0P28_11775) ruvA 2311984..2312577 (-) 594 WP_003066922.1 Holliday junction branch migration protein RuvA Machinery gene
  M0P28_RS11780 (M0P28_11780) hexB 2312579..2314522 (-) 1944 WP_117479524.1 DNA mismatch repair endonuclease MutL Machinery gene
  M0P28_RS11785 (M0P28_11785) hexA 2314639..2317209 (-) 2571 WP_003066925.1 DNA mismatch repair protein MutS Machinery gene
  M0P28_RS11790 (M0P28_11790) - 2317196..2317552 (-) 357 WP_003066927.1 YlbF family regulator -
  M0P28_RS11795 (M0P28_11795) argR 2317549..2317986 (-) 438 WP_003066930.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73260.36 Da        Isoelectric Point: 5.0956

>NTDB_id=715323 M0P28_RS11780 WP_117479524.1 2312579..2314522(-) (hexB) [Streptococcus pasteurianus strain WUSP074]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEEAGLKKIQVTDSGEGIAQDDVALSLHRHATSK
IKNQADLFRIRTLGFRGEAIPSIASISHFTVKTATADENYGTLLVAKGGEIEKQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEVAFSLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMSLISS
AIAESLREQDLIPDALENLAKSSTRGLPKPEQTSLPLKQTDLYYDKERRDFFVKSDTVEEQPVQLFNEVDNSVKEVDKQQ
TSVKYAQRSEVDNQDDEHDNLDFKNKTKINKMIESLDNEESSTFPELDYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKY
EYYREKIGDVDSSLQQLLMPYLFEFSGADFIKLQEKMELLNQVGIYLEPYGNNTFILREHPIWMKEEEIETAVYEMCDML
LLTNEVSVKKYRAELAIMMSCKRSIKANHILDDYSARHLLVQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=715323 M0P28_RS11780 WP_117479524.1 2312579..2314522(-) (hexB) [Streptococcus pasteurianus strain WUSP074]
ATGAGTAAAATTATTGAGTTGCCAGAGGTTTTGGCTAACCAAATTGCAGCGGGTGAAGTTATTGAACGACCAGCTAGCGT
TGTCAAAGAATTGGTGGAAAATTCGATTGATGCAGGGAGCAGCCAAATCACCATTGAAATTGAAGAAGCTGGTTTAAAGA
AAATTCAAGTGACAGATAGTGGCGAAGGAATTGCTCAAGATGATGTTGCATTAAGTTTGCACCGCCATGCCACAAGTAAA
ATTAAAAATCAAGCTGACCTTTTCCGTATTAGGACGTTAGGTTTTCGTGGTGAAGCGATACCGTCAATTGCCTCCATTAG
TCATTTTACAGTCAAAACAGCAACGGCAGATGAAAATTATGGAACATTGCTAGTAGCCAAAGGTGGTGAAATCGAAAAAC
AAGAACCGATTTCTACACCCGTTGGAACCAAAATTACGGTTGAAAATCTCTTTTATAATACGCCAGCACGTCTTAAATAC
ATGAAAAGTCTCCAATCCGAATTAGCTCATATTGTTGATGTGGTGAATCGTTTGAGTTTGGCGCACCCAGAGGTAGCTTT
TAGCTTGATTAATGATGGTCGTCAAATGACAACAACATCTGGTACTGGTGATTTGCGACAAGCAATTGCTGGTATTTATG
GGCTTAATACGGCTAAAAAAATGATTGAGATTTCGAATGCTGACCTCGATTTTGAAGTGTCTGGTTACATTAGTCTGCCA
GAATTGACACGAGCGAACCGAAACTATATTACGATTTTGATTAACGGTCGTTATATTAAAAACTTTTTGCTCAATCGTGC
GATTTTGGACGGTTATGGTTCAAAATTGATGGTGGGACGTTTTCCGATTGCTGTTATCGACATTCAAATCGACCCTTATT
TAGCTGATGTCAATGTTCACCCAACGAAGCAAGAAGTTCGTATTTCAAAGGAAAAAGAATTAATGAGCTTAATCAGCTCT
GCTATTGCAGAGAGTCTGCGTGAGCAAGATTTGATACCTGATGCTCTAGAAAATCTGGCGAAATCAAGCACACGTGGGCT
TCCGAAACCAGAGCAAACGAGCTTGCCGTTGAAACAAACAGACCTTTATTATGATAAAGAACGTCGTGATTTCTTTGTTA
AGTCAGATACGGTTGAAGAGCAACCAGTACAGTTATTCAATGAGGTTGACAACTCTGTCAAGGAAGTTGACAAGCAACAA
ACATCAGTGAAATATGCGCAGCGTTCCGAAGTAGATAATCAAGATGATGAACATGATAATCTCGATTTTAAAAACAAGAC
AAAAATCAATAAGATGATTGAAAGTCTTGATAATGAGGAGTCATCAACTTTCCCAGAATTAGATTATTTCGGACAAATGC
ACGGAACGTATCTTTTTGCACAGGGAAATGGTGGGCTTTATATCATTGACCAACACGCTGCTCAAGAACGTGTTAAATAT
GAATATTATCGTGAGAAAATCGGCGACGTTGACAGCTCTTTACAGCAGCTTCTCATGCCATACCTTTTTGAGTTTTCTGG
AGCTGATTTTATTAAGTTGCAAGAAAAAATGGAGCTGTTAAATCAAGTTGGTATTTATCTAGAACCATATGGAAACAACA
CTTTTATTCTCCGTGAACACCCAATTTGGATGAAAGAAGAGGAAATTGAGACGGCTGTTTATGAGATGTGTGATATGCTG
TTGTTGACAAATGAAGTATCGGTGAAGAAATATCGTGCAGAATTGGCAATCATGATGTCATGCAAACGCTCAATCAAAGC
GAATCACATTCTTGATGATTATTCCGCCCGACATCTTTTGGTTCAGTTATCACAATGTAAGAATCCTTATAACTGTCCAC
ATGGACGTCCAGTTCTTGTCAACTTTACCAAAGCTGACATGGAAAAAATGTTCCGCCGTATTCAAGAAAATCACACAAGT
TTAAGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-119)

MutL C terminal dimerisation domain (MutL_C)

(449-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.75

100

0.714