Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   M0P28_RS02525 Genome accession   NZ_CP116958
Coordinates   461342..461986 (+) Length   214 a.a.
NCBI ID   WP_013851527.1    Uniprot ID   F5X535
Organism   Streptococcus pasteurianus strain WUSP074     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 456342..466986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0P28_RS02505 (M0P28_02505) - 456929..457666 (+) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  M0P28_RS02510 (M0P28_02510) pknB 457666..459546 (+) 1881 WP_117479652.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  M0P28_RS02515 (M0P28_02515) liaF 459641..460336 (+) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  M0P28_RS02520 (M0P28_02520) - 460333..461358 (+) 1026 WP_117479650.1 sensor histidine kinase -
  M0P28_RS02525 (M0P28_02525) vraR 461342..461986 (+) 645 WP_013851527.1 response regulator transcription factor Regulator
  M0P28_RS02530 (M0P28_02530) - 462104..463504 (+) 1401 WP_069789204.1 Cof-type HAD-IIB family hydrolase -
  M0P28_RS02535 (M0P28_02535) - 463504..463860 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  M0P28_RS02540 (M0P28_02540) cysK 463973..464902 (-) 930 WP_003063544.1 cysteine synthase A -
  M0P28_RS02545 (M0P28_02545) - 465006..465632 (-) 627 WP_003063547.1 YigZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23953.74 Da        Isoelectric Point: 4.6633

>NTDB_id=715245 M0P28_RS02525 WP_013851527.1 461342..461986(+) (vraR) [Streptococcus pasteurianus strain WUSP074]
MTQKIKIILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=715245 M0P28_RS02525 WP_013851527.1 461342..461986(+) (vraR) [Streptococcus pasteurianus strain WUSP074]
ATGACCCAGAAAATTAAAATTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGCTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTCGGCGAAGCTGGAAATGGTTTAGACGGTATTAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCGACATTGAAGCTTCTGGAAGAATGGAAAGAAGCTAAG
ATTCTTGTCTTAACATCTTACCTTGATAATGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAACCAAACTATTGCTGATGAGTTATTTATCTCACTAAAGACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTCGATGACCGTACACAAGCAGTCGTTTACGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F5X535

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.942

96.262

0.5
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.397