Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   M0P24_RS08365 Genome accession   NZ_CP116957
Coordinates   1646796..1647440 (-) Length   214 a.a.
NCBI ID   WP_013851527.1    Uniprot ID   F5X535
Organism   Streptococcus pasteurianus strain WUSP070     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1641796..1652440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0P24_RS08345 (M0P24_08345) - 1643149..1643775 (+) 627 WP_048791291.1 YigZ family protein -
  M0P24_RS08350 (M0P24_08350) cysK 1643879..1644808 (+) 930 WP_117508847.1 cysteine synthase A -
  M0P24_RS08355 (M0P24_08355) - 1644921..1645277 (-) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  M0P24_RS08360 (M0P24_08360) - 1645277..1646677 (-) 1401 WP_003063536.1 Cof-type HAD-IIB family hydrolase -
  M0P24_RS08365 (M0P24_08365) vraR 1646796..1647440 (-) 645 WP_013851527.1 response regulator transcription factor Regulator
  M0P24_RS08370 (M0P24_08370) - 1647424..1648449 (-) 1026 WP_013851526.1 sensor histidine kinase -
  M0P24_RS08375 (M0P24_08375) liaF 1648446..1649141 (-) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  M0P24_RS08380 (M0P24_08380) pknB 1649236..1651116 (-) 1881 WP_117508846.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  M0P24_RS08385 (M0P24_08385) - 1651116..1651853 (-) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23953.74 Da        Isoelectric Point: 4.6633

>NTDB_id=715173 M0P24_RS08365 WP_013851527.1 1646796..1647440(-) (vraR) [Streptococcus pasteurianus strain WUSP070]
MTQKIKIILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=715173 M0P24_RS08365 WP_013851527.1 1646796..1647440(-) (vraR) [Streptococcus pasteurianus strain WUSP070]
ATGACCCAGAAAATTAAAATTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGTTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTCGGCGAAGCTGGAAATGGTTTAGATGGCATTAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCGACATTGAAGCTTCTGGAAGAATGGAAAGAAGCTAAG
ATTCTTGTCTTAACATCTTACCTTGATAATGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAACCAAACTATTGCTGATGAGTTATTTATCTCACTAAAGACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTCGATGACCGTACACAAGCAGTCGTTTACGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F5X535

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.942

96.262

0.5
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.397