Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PQH37_RS15425 Genome accession   NZ_CP116948
Coordinates   3034157..3034813 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CUVET21-PYO5     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3029157..3039813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQH37_RS15395 (PQH37_15325) yecA 3030409..3031074 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  PQH37_RS15415 (PQH37_15345) pgsA 3031723..3032271 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PQH37_RS15420 (PQH37_15350) uvrC 3032328..3034160 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PQH37_RS15425 (PQH37_15355) letA 3034157..3034813 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PQH37_RS15430 (PQH37_15360) yecU 3035109..3035285 (+) 177 WP_001307856.1 protein YecU -
  PQH37_RS15435 (PQH37_15365) yecF 3035272..3035496 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PQH37_RS15440 (PQH37_15370) sdiA 3035564..3036286 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  PQH37_RS15445 (PQH37_15375) tcyN 3036516..3037268 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PQH37_RS15450 (PQH37_15380) tcyL 3037265..3037933 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PQH37_RS15455 (PQH37_15385) dcyD 3037948..3038934 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=715068 PQH37_RS15425 WP_000611328.1 3034157..3034813(-) (letA) [Escherichia coli strain CUVET21-PYO5]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=715068 PQH37_RS15425 WP_000611328.1 3034157..3034813(-) (letA) [Escherichia coli strain CUVET21-PYO5]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482