Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NQZ88_RS02025 Genome accession   NZ_CP102152
Coordinates   385234..385923 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain DNS11     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 380234..390923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ88_RS02000 (NQZ88_02000) - 380563..381906 (+) 1344 WP_257116224.1 DEAD/DEAH box helicase -
  NQZ88_RS02005 (NQZ88_02005) - 381924..382148 (+) 225 WP_002936682.1 DUF4059 family protein -
  NQZ88_RS02010 (NQZ88_02010) trxB 382162..383079 (+) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  NQZ88_RS02015 (NQZ88_02015) - 383089..383628 (+) 540 WP_024385904.1 DUF177 domain-containing protein -
  NQZ88_RS02020 (NQZ88_02020) gndA 383725..385152 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  NQZ88_RS02025 (NQZ88_02025) covR 385234..385923 (+) 690 WP_012027645.1 DNA-binding response regulator Regulator
  NQZ88_RS02030 (NQZ88_02030) - 386013..387143 (+) 1131 WP_012027644.1 AI-2E family transporter -
  NQZ88_RS02035 (NQZ88_02035) nrdR 387215..387706 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  NQZ88_RS02040 (NQZ88_02040) - 387693..388844 (+) 1152 WP_074389435.1 replication initiation/membrane attachment protein -
  NQZ88_RS02045 (NQZ88_02045) dnaI 388844..389743 (+) 900 WP_002938337.1 primosomal protein DnaI -
  NQZ88_RS02050 (NQZ88_02050) - 389740..390453 (+) 714 WP_074389436.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=715049 NQZ88_RS02025 WP_012027645.1 385234..385923(+) (covR) [Streptococcus suis strain DNS11]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=715049 NQZ88_RS02025 WP_012027645.1 385234..385923(+) (covR) [Streptococcus suis strain DNS11]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACTGAAGTTAGTCAATATGGGGAGGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432