Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   NQZ91_RS09890 Genome accession   NZ_CP102145
Coordinates   1973816..1975108 (+) Length   430 a.a.
NCBI ID   WP_172094579.1    Uniprot ID   -
Organism   Streptococcus suis strain DNS20     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1971224..2005826 1973816..1975108 within 0


Gene organization within MGE regions


Location: 1971224..2005826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ91_RS09880 (NQZ91_09880) cysK 1972110..1973036 (-) 927 WP_105111234.1 cysteine synthase A -
  NQZ91_RS09885 (NQZ91_09885) - 1973127..1973759 (-) 633 WP_170238725.1 YigZ family protein -
  NQZ91_RS09890 (NQZ91_09890) comFA/cflA 1973816..1975108 (+) 1293 WP_172094579.1 DEAD/DEAH box helicase Machinery gene
  NQZ91_RS09895 (NQZ91_09895) - 1975101..1975766 (+) 666 WP_257117463.1 ComF family protein -
  NQZ91_RS09900 (NQZ91_09900) hpf 1975843..1976385 (+) 543 WP_105111237.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  NQZ91_RS09905 (NQZ91_09905) - 1976605..1976931 (+) 327 WP_125265373.1 hypothetical protein -
  NQZ91_RS09910 (NQZ91_09910) - 1977047..1980130 (+) 3084 WP_257117464.1 DEAD/DEAH box helicase -
  NQZ91_RS09915 (NQZ91_09915) - 1980215..1980874 (+) 660 WP_105161271.1 hypothetical protein -
  NQZ91_RS09920 (NQZ91_09920) murC 1980876..1982207 (+) 1332 WP_105111241.1 UDP-N-acetylmuramate--L-alanine ligase -
  NQZ91_RS09925 (NQZ91_09925) - 1982251..1982736 (+) 486 WP_125265369.1 GNAT family N-acetyltransferase -
  NQZ91_RS09930 (NQZ91_09930) - 1982751..1983113 (+) 363 WP_257117466.1 TIGR02328 family protein -
  NQZ91_RS09935 (NQZ91_09935) - 1983266..1983727 (+) 462 WP_105111243.1 GNAT family N-acetyltransferase -
  NQZ91_RS09940 (NQZ91_09940) - 1983743..1983991 (-) 249 Protein_1921 DNA cytosine methyltransferase -
  NQZ91_RS09945 (NQZ91_09945) - 1983990..1984489 (+) 500 Protein_1922 DUF4143 domain-containing protein -
  NQZ91_RS09950 (NQZ91_09950) - 1984511..1985770 (-) 1260 WP_257117467.1 hydroxymethylglutaryl-CoA reductase, degradative -
  NQZ91_RS09955 (NQZ91_09955) - 1985830..1986987 (-) 1158 WP_257117468.1 hydroxymethylglutaryl-CoA synthase -
  NQZ91_RS09960 (NQZ91_09960) - 1987013..1988197 (-) 1185 WP_257117469.1 acetyl-CoA C-acetyltransferase -
  NQZ91_RS09965 (NQZ91_09965) - 1988481..1989173 (+) 693 WP_257117470.1 phosphoglycerate mutase -
  NQZ91_RS09970 (NQZ91_09970) - 1989446..1990147 (+) 702 WP_257105002.1 discoidin domain-containing protein -
  NQZ91_RS11180 - 1990278..1990361 (+) 84 WP_394736257.1 LPXTG cell wall anchor domain-containing protein -
  NQZ91_RS09975 (NQZ91_09975) - 1990520..1990903 (+) 384 WP_105111248.1 VOC family protein -
  NQZ91_RS09980 (NQZ91_09980) - 1991036..1992433 (+) 1398 WP_257104780.1 polysaccharide deacetylase family protein -
  NQZ91_RS09985 (NQZ91_09985) - 1992593..1993948 (+) 1356 WP_172067166.1 6-phospho-beta-glucosidase -
  NQZ91_RS09990 (NQZ91_09990) - 1993948..1995348 (+) 1401 WP_105123466.1 glycoside hydrolase family 1 protein -
  NQZ91_RS09995 (NQZ91_09995) - 1995359..1996450 (+) 1092 WP_105111252.1 DUF871 domain-containing protein -
  NQZ91_RS10000 (NQZ91_10000) - 1996576..1998633 (+) 2058 WP_257117471.1 BglG family transcription antiterminator -
  NQZ91_RS10005 (NQZ91_10005) - 1998810..2000012 (+) 1203 WP_306455656.1 IS110 family transposase -
  NQZ91_RS10010 (NQZ91_10010) - 2000213..2000524 (+) 312 WP_105111254.1 PTS sugar transporter subunit IIB -
  NQZ91_RS10015 (NQZ91_10015) - 2000526..2000843 (+) 318 WP_105111255.1 PTS lactose/cellobiose transporter subunit IIA -
  NQZ91_RS10020 (NQZ91_10020) - 2000888..2001325 (+) 438 WP_172009446.1 DUF3284 domain-containing protein -
  NQZ91_RS10025 (NQZ91_10025) - 2001484..2002860 (+) 1377 WP_105111257.1 PTS sugar transporter subunit IIC -
  NQZ91_RS10030 (NQZ91_10030) - 2003055..2004137 (-) 1083 WP_105111258.1 DEAD/DEAH box helicase -
  NQZ91_RS10035 (NQZ91_10035) - 2004134..2005114 (-) 981 WP_257117473.1 Gfo/Idh/MocA family protein -
  NQZ91_RS10040 (NQZ91_10040) udk 2005197..2005826 (+) 630 WP_105123473.1 uridine kinase -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48905.27 Da        Isoelectric Point: 8.0831

>NTDB_id=714971 NQZ91_RS09890 WP_172094579.1 1973816..1975108(+) (comFA/cflA) [Streptococcus suis strain DNS20]
MKELENYYGRLFTKYQLTAEERQAAQTLPSMTEGGACFRCSTAFSDRHRLPNGAYYCRECILLGRVRSDEELYYFPQQDF
PENACLKWSGQLTDWQQKISNGLCANIEKRRPTLVHAVTGAGKTEMIYHAVAQVIDQGGAVCLASPRIDVCIELYKRLQQ
DFAVPISLLHGQSDPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAVDNAVKADGLQVFLTATSTDEL
DRKVKSGQLERLSLPRRFHGNPLIVPEKVWFSQFDQSLKKDKLVVKLKKAIRNQRKTSFPLLIFLPEISKGQEFVAILER
EFPDEKIGFVSSQTENRLEIVQGFRDRTITILVSTTILERGVTFPMVDVMVVQANHYLYTSSSLVQIGGRVGRSMDRPTG
LLLFFHEGSTRAIEKAIAEIKFMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=714971 NQZ91_RS09890 WP_172094579.1 1973816..1975108(+) (comFA/cflA) [Streptococcus suis strain DNS20]
ATGAAAGAATTAGAAAATTATTATGGACGACTGTTTACCAAGTATCAATTGACAGCTGAAGAGCGCCAAGCAGCTCAGAC
CTTACCTAGCATGACAGAGGGGGGCGCTTGTTTTCGTTGTTCGACTGCATTTTCGGACCGCCATCGTTTACCAAACGGGG
CCTACTATTGCCGAGAATGTATCCTGCTAGGCAGGGTGCGGTCAGATGAGGAACTCTATTATTTTCCCCAGCAGGATTTC
CCAGAAAATGCCTGTCTCAAGTGGTCTGGTCAGCTGACTGATTGGCAGCAGAAGATTTCAAACGGGCTCTGTGCCAATAT
TGAAAAAAGGCGGCCGACCTTGGTTCATGCCGTGACGGGGGCTGGAAAGACGGAGATGATTTACCATGCAGTAGCGCAAG
TCATTGACCAGGGCGGAGCAGTTTGTCTGGCCAGTCCCAGAATTGATGTCTGTATCGAGCTTTATAAGCGGCTGCAACAA
GATTTCGCTGTTCCCATCAGTCTCCTTCATGGTCAGTCGGATCCTTATTTTCGGACGCCGCTTGTGGTCGCTACCACCCA
CCAGTTGCTCAAGTTCTACCAGGCCTTTGATTTGGTCTTAATCGATGAGGTGGATGCCTTTCCCTATGCGGACAATCCCA
TGCTCTACCGGGCAGTAGACAATGCCGTCAAAGCAGACGGGCTCCAGGTTTTCCTGACAGCGACCTCGACGGATGAGCTG
GATAGGAAGGTAAAATCCGGCCAATTAGAACGGCTCAGTTTGCCCAGACGCTTTCACGGCAATCCCTTGATTGTGCCAGA
AAAGGTCTGGTTCAGCCAATTTGACCAGAGCCTGAAAAAGGACAAGCTGGTTGTCAAGCTCAAGAAAGCTATCAGAAACC
AGCGAAAAACAAGTTTTCCCTTGCTGATTTTTCTGCCAGAAATTTCCAAAGGCCAGGAATTTGTAGCGATTTTGGAGCGA
GAATTTCCTGATGAGAAAATCGGTTTTGTTTCTAGTCAGACGGAAAATCGACTGGAGATTGTTCAAGGTTTTCGCGACCG
CACCATTACCATCCTGGTTTCAACAACGATTCTGGAGCGAGGTGTGACCTTTCCCATGGTTGATGTCATGGTAGTCCAGG
CCAACCACTATCTCTATACGTCGTCCAGTTTGGTGCAGATTGGAGGTCGAGTCGGACGGTCCATGGATCGTCCCACAGGC
TTGCTCCTCTTTTTTCATGAGGGTTCGACCCGTGCCATTGAAAAAGCAATCGCTGAAATCAAATTTATGAATAAGGAGGC
CGGCTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(293-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

68.677

100

0.688
  comFA/cflA Streptococcus mitis NCTC 12261

68.445

100

0.686
  comFA/cflA Streptococcus pneumoniae D39

67.517

100

0.677
  comFA/cflA Streptococcus pneumoniae R6

67.517

100

0.677
  comFA/cflA Streptococcus pneumoniae TIGR4

67.517

100

0.677
  comFA/cflA Streptococcus pneumoniae Rx1

67.517

100

0.677
  comFA Lactococcus lactis subsp. cremoris KW2

52.792

91.628

0.484
  comFA Latilactobacillus sakei subsp. sakei 23K

38.605

100

0.386