Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NQZ95_RS05905 Genome accession   NZ_CP102138
Coordinates   1173880..1175259 (-) Length   459 a.a.
NCBI ID   WP_002935290.1    Uniprot ID   A0A0Z8I1B6
Organism   Streptococcus suis strain M102942_S11     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1168880..1180259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ95_RS05885 (NQZ95_05885) - 1170137..1170727 (-) 591 WP_029188321.1 class I SAM-dependent methyltransferase -
  NQZ95_RS05890 (NQZ95_05890) coaA 1170836..1171756 (+) 921 WP_002935283.1 type I pantothenate kinase -
  NQZ95_RS05895 (NQZ95_05895) rpsT 1171815..1172063 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  NQZ95_RS05900 (NQZ95_05900) - 1172327..1173556 (-) 1230 WP_248017884.1 transglutaminase domain-containing protein -
  NQZ95_RS05905 (NQZ95_05905) ciaH 1173880..1175259 (-) 1380 WP_002935290.1 cell wall metabolism sensor histidine kinase WalK Regulator
  NQZ95_RS05910 (NQZ95_05910) ciaR 1175252..1175923 (-) 672 WP_024385291.1 response regulator transcription factor Regulator
  NQZ95_RS10515 - 1176117..1176452 (-) 336 Protein_1133 hypothetical protein -
  NQZ95_RS05920 (NQZ95_05920) phoU 1176618..1177274 (-) 657 WP_024394630.1 phosphate signaling complex protein PhoU -
  NQZ95_RS05925 (NQZ95_05925) pstB 1177303..1178061 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ95_RS05930 (NQZ95_05930) pstB 1178073..1178876 (-) 804 WP_002937615.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ95_RS05935 (NQZ95_05935) pstA 1178901..1179788 (-) 888 WP_002937616.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51921.60 Da        Isoelectric Point: 6.8879

>NTDB_id=714736 NQZ95_RS05905 WP_002935290.1 1173880..1175259(-) (ciaH) [Streptococcus suis strain M102942_S11]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSTPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQMAANIKDKLVCFTVIDNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=714736 NQZ95_RS05905 WP_002935290.1 1173880..1175259(-) (ciaH) [Streptococcus suis strain M102942_S11]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCACGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGGTTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGGTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAAGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATGGCAGCTAATATCAAGGATAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGCC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8I1B6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

48.791

99.129

0.484