Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL422_RS10280 Genome accession   NZ_CP116931
Coordinates   2010382..2011038 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MLI106K1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2005382..2016038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL422_RS10250 (NL422_010250) dcyD 2006261..2007247 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NL422_RS10255 (NL422_010255) tcyL 2007262..2007930 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NL422_RS10260 (NL422_010260) tcyN 2007927..2008679 (+) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL422_RS10265 (NL422_010265) sdiA 2008909..2009631 (+) 723 WP_016236716.1 transcriptional regulator SdiA -
  NL422_RS10270 (NL422_010270) yecF 2009699..2009923 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL422_RS10275 (NL422_010275) yecU 2009910..2010086 (-) 177 WP_032149425.1 protein YecU -
  NL422_RS10280 (NL422_010280) letA 2010382..2011038 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL422_RS10285 (NL422_010285) uvrC 2011035..2012867 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NL422_RS10290 (NL422_010290) pgsA 2012924..2013472 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL422_RS10310 (NL422_010310) yecA 2014121..2014786 (+) 666 WP_072617294.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=714542 NL422_RS10280 WP_000611335.1 2010382..2011038(+) (letA) [Escherichia coli strain MLI106K1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=714542 NL422_RS10280 WP_000611335.1 2010382..2011038(+) (letA) [Escherichia coli strain MLI106K1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATTATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486