Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL420_RS10020 Genome accession   NZ_CP116925
Coordinates   1935396..1936052 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MLI104K2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1930396..1941052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL420_RS09990 (NL420_009990) dcyD 1931276..1932262 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NL420_RS09995 (NL420_009995) tcyL 1932277..1932945 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NL420_RS10000 (NL420_010000) tcyN 1932942..1933694 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL420_RS10005 (NL420_010005) sdiA 1933924..1934646 (+) 723 WP_001154275.1 transcriptional regulator SdiA -
  NL420_RS10010 (NL420_010010) yecF 1934713..1934937 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL420_RS10015 (NL420_010015) yecU 1934924..1935100 (-) 177 WP_032160694.1 protein YecU -
  NL420_RS10020 (NL420_010020) letA 1935396..1936052 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL420_RS10025 (NL420_010025) uvrC 1936049..1937881 (+) 1833 WP_072667239.1 excinuclease ABC subunit UvrC Machinery gene
  NL420_RS10030 (NL420_010030) pgsA 1937938..1938486 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL420_RS10050 (NL420_010050) - 1939183..1939923 (-) 741 WP_032289701.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=714382 NL420_RS10020 WP_000611328.1 1935396..1936052(+) (letA) [Escherichia coli strain MLI104K2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=714382 NL420_RS10020 WP_000611328.1 1935396..1936052(+) (letA) [Escherichia coli strain MLI104K2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482