Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NQZ84_RS04935 Genome accession   NZ_CP102094
Coordinates   993522..994748 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain 12RC1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 988522..999748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS04910 (NQZ84_04910) - 988841..990148 (-) 1308 WP_044752124.1 excalibur calcium-binding domain-containing protein -
  NQZ84_RS04915 (NQZ84_04915) - 990283..990465 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  NQZ84_RS04920 (NQZ84_04920) lepA 990515..992347 (-) 1833 WP_002943192.1 translation elongation factor 4 -
  NQZ84_RS04925 (NQZ84_04925) ndk 992443..992856 (-) 414 WP_024380696.1 nucleoside-diphosphate kinase -
  NQZ84_RS04930 (NQZ84_04930) yihA 992879..993466 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NQZ84_RS04935 (NQZ84_04935) clpX 993522..994748 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NQZ84_RS04940 (NQZ84_04940) - 994946..995458 (-) 513 WP_257047327.1 dihydrofolate reductase -
  NQZ84_RS04945 (NQZ84_04945) - 995771..996610 (-) 840 WP_257047328.1 thymidylate synthase -
  NQZ84_RS04950 (NQZ84_04950) - 996663..996965 (-) 303 WP_257047329.1 hypothetical protein -
  NQZ84_RS04955 (NQZ84_04955) - 996978..997256 (-) 279 WP_257047331.1 hypothetical protein -
  NQZ84_RS04960 (NQZ84_04960) - 997382..998341 (-) 960 WP_044679583.1 ROK family glucokinase -
  NQZ84_RS04965 (NQZ84_04965) - 998437..998772 (-) 336 WP_002934966.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=714298 NQZ84_RS04935 WP_002934974.1 993522..994748(-) (clpX) [Streptococcus suis strain 12RC1]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=714298 NQZ84_RS04935 WP_002934974.1 993522..994748(-) (clpX) [Streptococcus suis strain 12RC1]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTT
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAGAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACAGAACCGAAGAATGCTCTTGTAAAACAATACCAAACCCTCTTGTCTTACGATGATGTAGAGTTGGATTTTGACGAGGA
TGCCTTATTAGCAATTGCAGAAAAGGCAATTGAGCGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574