Detailed information NTG0714230

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NF398_RS07505
• Genome accession: NZ_CP102087
• Coordinates: 1526599..1527645 (-)
• Length: 348 a.a.
• NCBI ID: WP_002435929.1
• Uniprot ID: A0A0S4MEI3
• Organism: Staphylococcus capitis subsp. capitis strain K1-2-2-23
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1521599..1532645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NF398_RS07475	-	1521968..1523209 (-)	1242	WP_023350031.1	aminopeptidase	-
NF398_RS07480	-	1523223..1523429 (-)	207	WP_002435959.1	DUF1128 domain-containing protein	-
NF398_RS07485	-	1523570..1524034 (+)	465	WP_002435947.1	low molecular weight protein-tyrosine-phosphatase	-
NF398_RS07490	-	1524041..1524325 (+)	285	WP_002435890.1	hypothetical protein	-
NF398_RS07495	-	1524662..1525915 (+)	1254	WP_002435884.1	YihY/virulence factor BrkB family protein	-
NF398_RS07500	vraR	1525980..1526609 (-)	630	WP_002469716.1	two-component system response regulator VraR	Regulator
NF398_RS07505	vraS	1526599..1527645 (-)	1047	WP_002435929.1	sensor histidine kinase	Regulator
NF398_RS07510	liaF	1527642..1528343 (-)	702	WP_002435891.1	cell wall-active antibiotics response protein LiaF	-
NF398_RS07515	-	1528358..1528744 (-)	387	WP_002453601.1	hypothetical protein	-
NF398_RS07520	map	1528889..1529644 (-)	756	WP_002435911.1	type I methionyl aminopeptidase	-
NF398_RS07525	-	1529818..1530807 (+)	990	WP_002435886.1	aromatic acid exporter family protein	-
NF398_RS07530	-	1530885..1531427 (-)	543	WP_023350030.1	hypothetical protein	-
NF398_RS07535	-	1531656..1532381 (-)	726	WP_002469718.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40136.57 Da
• Isoelectric Point: 6.0600

>NTDB_id=714230 NF398_RS07505 WP_002435929.1 1526599..1527645(-) (vraS) [Staphylococcus capitis subsp. capitis strain K1-2-2-23]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNILIILLCIIVGSVLAYKINQQNDWLKS
QIERSIEGETVGINDQNLELYSETLEIYHTLVPLNQELHRLRMKTQNMTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGSKVTVELFNKEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDESNGD

Nucleotide

• Length: 1047 bp

>NTDB_id=714230 NF398_RS07505 WP_002435929.1 1526599..1527645(-) (vraS) [Staphylococcus capitis subsp. capitis strain K1-2-2-23]
ATGAATCACTACTTGAGAGCAATTGGTTCAATGCTAATACTTGTATATAGCATGCTAACTGCTTTTTTATTCATTGATAA
GGTGTTCGTCAATATTATTTATTTTCAAGGGATGTTTTACACCCAAATTTTTGGAATACCAGTATTTTTATTCCTAAATA
TATTAATCATCTTACTATGTATTATCGTTGGCTCTGTGTTAGCGTATAAAATCAATCAACAAAATGATTGGCTTAAGTCA
CAAATTGAAAGGTCTATTGAAGGTGAAACAGTAGGCATAAATGATCAAAACCTAGAGTTATACAGTGAAACGTTAGAAAT
TTACCATACTTTAGTTCCTTTAAATCAAGAATTACACCGATTGAGAATGAAAACGCAGAATATGACCAATGAAAATTATA
ATATGAATGATGTAAAAGTGAAGAAAATTATTGAAGACGAACGTCAACGTTTAGCAAGAGAACTACATGACTCAGTTAGT
CAGCAACTATTTGCAGCAAGTATGATGTTGTCAGCGATTAAAGAGTCAAAATTAGAACCACCTTTAGACCAACAAATACC
TGTACTAGAGAAGATGGTTCAAGACTCTCAGCTCGAAATGAGAGCATTATTATTACATCTAAGACCTATTGGTTTGAAAG
ACAAATCATTAGGAGAGGGTATTAAAGATTTAGTCATTGATCTTCAAAAGAAAGTCCCTATGAAAGTTGTTCATGAAATT
CAAGATTTCAAAGTACCAAAAGGGATAGAAGATCATTTGTTTAGAATCACCCAAGAGGCTATTTCTAATACATTACGACA
CTCTAATGGTTCTAAGGTAACAGTTGAATTATTTAATAAAGAAGATTATTTACTACTTAGAATTCAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTTGAACAGAGTTATGGATTAAAAAATATGAGAGAACGTGCTTTAGAGATTGGTGCCACA
TTCCATATCGTATCGTTACCGGATTCAGGTACGAGAATAGAAGTTAAAGCACCATTGAATAAGGAGGATGAATCAAATGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A0S4MEI3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.586	98.563	0.922