Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL406_RS09675 Genome accession   NZ_CP116913
Coordinates   1860804..1861460 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MLI023K1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1855804..1866460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL406_RS09645 (NL406_009645) dcyD 1856684..1857670 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NL406_RS09650 (NL406_009650) tcyL 1857685..1858353 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  NL406_RS09655 (NL406_009655) tcyN 1858350..1859102 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL406_RS09660 (NL406_009660) sdiA 1859332..1860054 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  NL406_RS09665 (NL406_009665) yecF 1860121..1860345 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL406_RS09670 (NL406_009670) yecU 1860332..1860508 (-) 177 WP_001326718.1 protein YecU -
  NL406_RS23285 - 1860591..1860662 (-) 72 Protein_1747 transcriptional regulator -
  NL406_RS09675 (NL406_009675) letA 1860804..1861460 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL406_RS09680 (NL406_009680) uvrC 1861457..1863289 (+) 1833 WP_054518559.1 excinuclease ABC subunit UvrC Machinery gene
  NL406_RS09685 (NL406_009685) pgsA 1863346..1863894 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL406_RS09705 (NL406_009705) yecA 1864544..1865209 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=714140 NL406_RS09675 WP_000611335.1 1860804..1861460(+) (letA) [Escherichia coli strain MLI023K1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=714140 NL406_RS09675 WP_000611335.1 1860804..1861460(+) (letA) [Escherichia coli strain MLI023K1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486