Detailed information    

insolico Bioinformatically predicted

Overview

Name   hdrM   Type   Regulator
Locus tag   NPS16_RS08535 Genome accession   NZ_CP101986
Coordinates   1808340..1809026 (+) Length   228 a.a.
NCBI ID   WP_002268420.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14     
Function   repress competence development; negative regulate HdrR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1803340..1814026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS08515 (NPS16_08515) - 1805411..1805632 (+) 222 WP_019312622.1 hypothetical protein -
  NPS16_RS08520 (NPS16_08520) - 1806022..1806966 (+) 945 WP_002262667.1 magnesium transporter CorA family protein -
  NPS16_RS08525 (NPS16_08525) - 1807186..1807848 (+) 663 WP_258968882.1 DUF1129 domain-containing protein -
  NPS16_RS08530 (NPS16_08530) hdrR 1807987..1808343 (+) 357 WP_002268419.1 LytTR family transcriptional regulator HdrR Regulator
  NPS16_RS08535 (NPS16_08535) hdrM 1808340..1809026 (+) 687 WP_002268420.1 hdrR negative regulator HdrM Regulator
  NPS16_RS08540 (NPS16_08540) - 1809034..1809753 (-) 720 WP_002273460.1 TraX family protein -
  NPS16_RS08545 (NPS16_08545) rpsR 1810072..1810311 (-) 240 WP_000068664.1 30S ribosomal protein S18 -
  NPS16_RS08550 (NPS16_08550) ssbA 1810341..1810835 (-) 495 WP_002261867.1 single-stranded DNA-binding protein Machinery gene
  NPS16_RS08555 (NPS16_08555) rpsF 1810853..1811143 (-) 291 WP_002261866.1 30S ribosomal protein S6 -
  NPS16_RS08560 (NPS16_08560) - 1811299..1811544 (-) 246 WP_002263367.1 hypothetical protein -
  NPS16_RS08565 (NPS16_08565) - 1811849..1812052 (+) 204 WP_002267523.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26101.17 Da        Isoelectric Point: 6.7581

>NTDB_id=713667 NPS16_RS08535 WP_002268420.1 1808340..1809026(+) (hdrM) [Streptococcus mutans strain COCC33-14]
MKKNYFWYGLLGLLALYLITIAFIPGFHIFFSNMLMLALFFMLIALSNRSIFFFFLALGFLSIYLKDIFHFDYSTGPLFT
GIIIIGVILNSFLKPHYSYSYKGNHYFNMKQNANYIDNETDVFLKTLFSENTSYVTSQELNKIIIDTKFGEQSVDLSQAQ
FMTDSPEIHIDISFGETNLRIPNNWKIINKTHSPFASISFSGFPSTNGDFINVTLTGTVAMGSLNIQY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=713667 NPS16_RS08535 WP_002268420.1 1808340..1809026(+) (hdrM) [Streptococcus mutans strain COCC33-14]
ATGAAAAAAAATTATTTTTGGTACGGTCTGCTTGGGCTTCTCGCACTTTACCTTATTACTATTGCTTTTATCCCGGGATT
TCATATTTTCTTTAGCAACATGTTGATGTTGGCTCTGTTCTTTATGTTAATAGCTTTGAGTAACAGGAGTATCTTCTTTT
TCTTTCTAGCCTTAGGTTTTCTTAGTATCTACTTGAAAGATATCTTTCATTTTGACTATTCTACCGGACCGCTTTTTACG
GGTATAATCATTATCGGCGTTATTTTAAATAGTTTCCTCAAACCACACTATTCTTATTCTTATAAAGGAAATCATTATTT
TAATATGAAACAAAATGCTAACTACATTGATAACGAAACAGATGTCTTTTTAAAAACACTTTTTTCTGAAAATACCAGTT
ATGTGACTTCTCAAGAATTAAATAAAATTATTATTGATACTAAGTTTGGAGAACAATCTGTTGATCTCTCTCAAGCTCAA
TTTATGACAGATTCTCCCGAAATTCATATAGATATTAGCTTTGGTGAAACCAATCTGCGTATTCCAAACAACTGGAAAAT
CATCAATAAAACTCACTCTCCCTTTGCTTCCATTTCATTTTCAGGTTTTCCTAGCACAAATGGTGATTTTATTAACGTTA
CATTGACTGGAACAGTGGCTATGGGATCTCTAAACATTCAATATTAA

Domains

Predicted by InterproScan.

Cell wall-active antibiotics response 4TMS YvqF (LiaF-like_C)

(128-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hdrM Streptococcus mutans UA159

99.123

100

0.991