Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   NPS16_RS02375 Genome accession   NZ_CP101986
Coordinates   490957..492258 (+) Length   433 a.a.
NCBI ID   WP_258969063.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 485957..497258
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS02355 (NPS16_02355) - 487107..487775 (+) 669 WP_002263030.1 fructose-6-phosphate aldolase -
  NPS16_RS02360 (NPS16_02360) - 487813..488904 (+) 1092 WP_032526185.1 glycerol dehydrogenase -
  NPS16_RS02365 (NPS16_02365) cysK 489238..490164 (-) 927 WP_002263028.1 cysteine synthase A -
  NPS16_RS02370 (NPS16_02370) - 490255..490884 (-) 630 WP_082999677.1 YigZ family protein -
  NPS16_RS02375 (NPS16_02375) comFA/cflA 490957..492258 (+) 1302 WP_258969063.1 DEAD/DEAH box helicase Machinery gene
  NPS16_RS02380 (NPS16_02380) - 492255..492920 (+) 666 WP_002270131.1 ComF family protein -
  NPS16_RS02385 (NPS16_02385) hpf 492999..493547 (+) 549 WP_002263024.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  NPS16_RS02390 (NPS16_02390) - 493671..494765 (+) 1095 WP_258969064.1 hypothetical protein -
  NPS16_RS02395 (NPS16_02395) - 494785..496485 (+) 1701 WP_258969065.1 zinc ribbon domain-containing protein -
  NPS16_RS02400 (NPS16_02400) - 496565..497200 (-) 636 WP_024785299.1 hypothetical protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49487.60 Da        Isoelectric Point: 9.9705

>NTDB_id=713637 NPS16_RS02375 WP_258969063.1 490957..492258(+) (comFA/cflA) [Streptococcus mutans strain COCC33-14]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLDFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRGKLPRSFLQQIRIQRQTQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=713637 NPS16_RS02375 WP_258969063.1 490957..492258(+) (comFA/cflA) [Streptococcus mutans strain COCC33-14]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGACTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGGTAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGACTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACTTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAAATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

Type III restriction enzyme, res subunit (ResIII)

(94-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae D39

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae R6

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae TIGR4

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

58.782

98.614

0.58
  comFA/cflA Streptococcus mitis SK321

58.314

98.614

0.575
  comFA Lactococcus lactis subsp. cremoris KW2

51.777

90.993

0.471
  comFA Latilactobacillus sakei subsp. sakei 23K

38.967

98.383

0.383