Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB/nlmE   Type   Regulator
Locus tag   NPS16_RS01320 Genome accession   NZ_CP101986
Coordinates   284139..285041 (+) Length   300 a.a.
NCBI ID   WP_002266018.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 279139..290041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS01295 (NPS16_01295) - 279183..279440 (+) 258 WP_025998437.1 hypothetical protein -
  NPS16_RS01300 (NPS16_01300) - 280541..280759 (+) 219 WP_019319873.1 Blp family class II bacteriocin -
  NPS16_RS01305 (NPS16_01305) - 280784..281188 (+) 405 WP_226730863.1 hypothetical protein -
  NPS16_RS01310 (NPS16_01310) - 281238..281414 (+) 177 WP_002284943.1 hypothetical protein -
  NPS16_RS01315 (NPS16_01315) comA/nlmT 281843..284125 (+) 2283 WP_002271629.1 peptide cleavage/export ABC transporter Regulator
  NPS16_RS01320 (NPS16_01320) comB/nlmE 284139..285041 (+) 903 WP_002266018.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  NPS16_RS01325 (NPS16_01325) - 285417..287084 (+) 1668 WP_002271628.1 transcription antiterminator -
  NPS16_RS01330 (NPS16_01330) ulaG 287664..288755 (+) 1092 WP_002263526.1 L-ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 34144.55 Da        Isoelectric Point: 10.4515

>NTDB_id=713629 NPS16_RS01320 WP_002266018.1 284139..285041(+) (comB/nlmE) [Streptococcus mutans strain COCC33-14]
MDPKFLQSAEFYRRRYHNFATLLIVPLVCLIIFLVIFLCFAKKEITVISTGEVAPTKVVDVIQSYSDSSIIKNNLDNNAA
VEKGDVLIEYSENASPNRQTEQKNIIKERQKREEKEKKKHRKSKKKKKSKSKKASKDKKKKSKDKESSSDDENETKKVSI
FASEDGIIHTNPKYDGANIIPKQTEIAQIYPDIQKTRKVLITYYASSDDVVSMKKGQTARLSLEKKGNDKVVIEGKINNV
ASSATTTKKGNLFKVTAKVKVSKKNSKLIKYGMTGKTVTVIDKKTYFDYFKDKLLHKMDN

Nucleotide


Download         Length: 903 bp        

>NTDB_id=713629 NPS16_RS01320 WP_002266018.1 284139..285041(+) (comB/nlmE) [Streptococcus mutans strain COCC33-14]
ATGGATCCTAAATTTTTACAAAGTGCAGAATTTTATAGGAGACGCTATCATAATTTTGCGACACTATTAATTGTTCCTTT
GGTCTGCTTGATTATCTTCTTGGTCATATTCCTTTGTTTTGCTAAAAAAGAAATTACAGTGATTTCTACTGGTGAAGTTG
CACCAACAAAGGTTGTAGATGTTATCCAATCTTACAGTGACAGTTCAATCATTAAAAATAATTTAGATAATAATGCAGCC
GTTGAGAAGGGAGACGTTTTAATTGAATATTCAGAAAATGCCAGTCCAAACCGTCAGACTGAACAAAAGAATATTATAAA
AGAAAGACAAAAACGAGAAGAGAAGGAAAAGAAAAAACACCGAAAGAGCAAGAAAAAGAAGAAGTCTAAGAGCAAGAAAG
CTTCCAAAGATAAGAAAAAGAAATCGAAAGACAAGGAAAGCAGCTCTGACGATGAAAATGAGACAAAAAAGGTTTCGATT
TTTGCTTCAGAAGATGGTATTATTCATACCAATCCCAAATATGATGGTGCCAATATTATTCCGAAGCAAACCGAGATTGC
TCAAATCTATCCTGATATTCAAAAAACAAGAAAAGTGTTAATCACCTATTATGCTTCTTCTGATGATGTTGTTTCTATGA
AAAAGGGGCAAACCGCTCGTCTTTCCTTGGAAAAAAAGGGAAATGACAAGGTTGTTATTGAAGGAAAAATTAACAATGTC
GCTTCATCAGCAACTACTACTAAAAAAGGAAATCTCTTTAAGGTTACTGCCAAAGTAAAGGTTTCTAAGAAAAATAGCAA
ACTCATCAAGTATGGTATGACAGGCAAGACAGTCACTGTCATTGATAAAAAGACTTATTTTGATTATTTCAAAGATAAAT
TACTGCATAAAATGGATAATTAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(160-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB/nlmE Streptococcus mutans UA159

99.667

100

0.997